Literature DB >> 6093260

Activation of the c-myb locus by viral insertional mutagenesis in plasmacytoid lymphosarcomas.

G L Shen-Ong, M Potter, J F Mushinski, S Lavu, E P Reddy.   

Abstract

Rearrangement in the c-myb locus of each of four independently derived BALB/c plasmacytoid lymphosarcoma (ABPL's) is due to the insertion of a defective Moloney murine leukemia virus (M-MuLV) into a 1.5-kilobase-pair stretch of cellular DNA at the 5' end of the v-myb-related sequences. This retroviral insertion is associated with abnormal transcription of myb sequences and probably represents a step in the neoplastic transformation of ABPL cells.

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Year:  1984        PMID： 6093260     DOI： 10.1126/science.6093260

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  51 in total

Review 1.  Mouse chromosome 10.

Authors:  B A Taylor; W N Frankel; R H Reeves
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

2.  Moloney murine leukemia virus-induced myeloid tumors in adult BALB/c mice: requirement of c-myb activation but lack of v-abl involvement.

Authors:  G L Shen-Ong; L Wolff
Journal:  J Virol       Date:  1987-12       Impact factor: 5.103

3.  Comparative molecular genetic analysis of lymphomas from six inbred mouse strains.

Authors:  M L Mucenski; H G Bedigian; M M Shull; N G Copeland; N A Jenkins
Journal:  J Virol       Date:  1988-03       Impact factor: 5.103

4.  Acute myeloid leukemia induction by amphotropic murine retrovirus (4070A): clonal integrations involve c-myb in some but not all leukemias.

Authors:  L Wolff; R Koller; W Davidson
Journal:  J Virol       Date:  1991-07       Impact factor: 5.103

Review 5.  Mouse chromosome 10.

Authors:  B A Taylor; M J Justice; R Reeves
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

6.  Activation of the c-ski oncogene by overexpression.

Authors:  C Colmenares; P Sutrave; S H Hughes; E Stavnezer
Journal:  J Virol       Date:  1991-09       Impact factor: 5.103

7.  Perturbed hemopoiesis and the generation of multipotential stem cell clones in src-infected bone marrow cultures is an indirect or transient effect of the oncogene.

Authors:  J A Wyke; A W Stoker; S Searle; E Spooncer; P Simmons; T M Dexter
Journal:  Mol Cell Biol       Date:  1986-03       Impact factor: 4.272

8.  5' long terminal repeats of myc-associated proviruses appear structurally intact but are functionally impaired in tumors induced by avian leukosis viruses.

Authors:  M M Goodenow; W S Hayward
Journal:  J Virol       Date:  1987-08       Impact factor: 5.103

9.  Aberrant splicing events that are induced by proviral integration: implications for myb oncogene activation.

Authors:  D Rosson; D Dugan; E P Reddy
Journal:  Proc Natl Acad Sci U S A       Date:  1987-05       Impact factor: 11.205

10.  Insertional activation of N-myc by endogenous Moloney-like murine retrovirus sequences in macrophage cell lines derived from myeloma cell line-macrophage hybrids.

Authors:  M Setoguchi; Y Higuchi; S Yoshida; N Nasu; Y Miyazaki; S Akizuki; S Yamamoto
Journal:  Mol Cell Biol       Date:  1989-10       Impact factor: 4.272
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