Literature DB >> 6093185

Radiation-induced crosslinking of cytosine.

M Dizdaroglu, M G Simic.   

Abstract

Formation of dimers upon gamma irradiation of cytosine, 2'-deoxycytidine, and 2'-deoxycytidine-5'-monophosphate in N2O-saturated aqueous solutions was found to be a major process. Quantitative measurements revealed that more than 50% of OH adduct radicals of cytosine undergo dimerization. Derivatized dimers and monomeric products were separated and tentatively identified by combined capillary gas chromatography-mass spectrometry.

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Year:  1984        PMID: 6093185

Source DB:  PubMed          Journal:  Radiat Res        ISSN: 0033-7587            Impact factor:   2.841


  8 in total

Review 1.  A review of conditions affecting the radiolysis due to 40K on nucleic acid bases and their derivatives adsorbed on clay minerals: implications in prebiotic chemistry.

Authors:  F G Mosqueira; G Albarran; A Negron-Mendoza
Journal:  Orig Life Evol Biosph       Date:  1996-02       Impact factor: 1.950

Review 2.  Current aspects on the radiation induced base damage in DNA.

Authors:  U Hagen
Journal:  Radiat Environ Biophys       Date:  1986       Impact factor: 1.925

3.  Tandem double CC-->TT mutations are produced by reactive oxygen species.

Authors:  T M Reid; L A Loeb
Journal:  Proc Natl Acad Sci U S A       Date:  1993-05-01       Impact factor: 11.205

4.  Major oxidative products of cytosine, 5-hydroxycytosine and 5-hydroxyuracil, exhibit sequence context-dependent mispairing in vitro.

Authors:  A A Purmal; Y W Kow; S S Wallace
Journal:  Nucleic Acids Res       Date:  1994-01-11       Impact factor: 16.971

5.  Free-radical reactions induced by OH-radical attack on cytosine-related compounds: a study by a method combining ESR, spin trapping and HPLC.

Authors:  W Hiraoka; M Kuwabara; F Sato; A Matsuda; T Ueda
Journal:  Nucleic Acids Res       Date:  1990-03-11       Impact factor: 16.971

6.  Yeast DNA polymerase zeta (zeta) is essential for error-free replication past thymine glycol.

Authors:  Robert E Johnson; Sung-Lim Yu; Satya Prakash; Louise Prakash
Journal:  Genes Dev       Date:  2003-01-01       Impact factor: 11.361

7.  Identification and characterization of a novel cross-link lesion in d(CpC) upon 365-nm irradiation in the presence of 2-methyl-1,4-naphthoquinone.

Authors:  Zhenjiu Liu; Yuan Gao; Yinsheng Wang
Journal:  Nucleic Acids Res       Date:  2003-09-15       Impact factor: 16.971

8.  Exposure to ionizing radiation reveals global dose- and time-dependent changes in the urinary metabolome of rat.

Authors:  Tytus D Mak; John B Tyburski; Kristopher W Krausz; John F Kalinich; Frank J Gonzalez; Albert J Fornace
Journal:  Metabolomics       Date:  2014-12-20       Impact factor: 4.290

  8 in total

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