| Literature DB >> 6092826 |
T Kouzarides, A T Bankier, B G Barrell.
Abstract
We report the nucleotide sequence of a BamHI-HindIII fragment of human cytomegalovirus containing the region (XbaI-HindIII) capable of transforming NIH3T3 cells. The single EcoRI site, shown to abolish transforming activity if cleaved, is present within an 8 base-pair inverted complementary repeat. Close to this sequence there is a small, potentially spliced, open reading frame possessing some of the signals involved in eukaryotic gene expression. Possible mechanisms of transformation, involving the inverted repeat sequence, are discussed.Entities:
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Year: 1983 PMID： 6092826
Source DB: PubMed Journal: Mol Biol Med ISSN： 0735-1313