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Literature DB >> 6092710

Association of poliovirus proteins with the endoplasmic reticulum.

Abstract

Poliovirus proteins, except P3-7c, are associated with the endoplasmic reticulum after extraction of the cytoplasm and centrifugation of membranes to equilibrium in sucrose gradients. Proteins P3-2, P2-X, and P3-9 are found preferentially among the rough endoplasmic reticulum, whereas P3-7c is located in smooth endoplasmic reticulum fractions. P3-7c is probably not membrane associated, since it can be separated from membranes after centrifugation in buffer. However, P3-4a, P2-5b, P2-X, and P3-9 are avidly bound to membranes and cannot be dislodged with high-ionic-strength buffer containing EDTA or 4 M urea. These proteins are digested by trypsin, indicating peripheral rather than internal localization.

Entities: Chemical Gene Species

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Year: 1984 PMID： 6092710 PMCID： PMC254596

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

23 in total

1. In vitro assembly of polioviruses. 3. Assembly of 14 S particles into empty capsids by poliovirus-infected HeLa cell membranes.

Authors: M Perlin; B A Phillips
Journal: Virology Date: 1973-05 Impact factor: 3.616

2. Proteins associated with the poliovirus RNA replication complex.

Authors: L A Caliguiri; A G Mosser
Journal: Virology Date: 1971-11 Impact factor: 3.616

3. Chemical and enzymatic characteristics of cytoplasmic membranes of poliovirus-infected HeLa cells.

Authors: A G Mosser; L A Caliguiri; A S Scheid; I Tamm
Journal: Virology Date: 1972-01 Impact factor: 3.616

4. Comparison of polysomal structures of uninfected and poliovirus infected HeLa cells.

Authors: M Roumiantzeff; J V Maizel; D F Summers
Journal: Virology Date: 1971-05 Impact factor: 3.616

5. Characterization of poliovirus-specific structures associated with cytoplasmic membranes.

Authors: L A Caliguiri; I Tamm
Journal: Virology Date: 1970-09 Impact factor: 3.616

6. The role of cytoplasmic membranes in poliovirus biosynthesis.

Authors: L A Caliguiri; I Tamm
Journal: Virology Date: 1970-09 Impact factor: 3.616

7. Cytopathology of Mengovirus infection. II. Proliferation of membranous cisternae.

Authors: K Amako; S Dales
Journal: Virology Date: 1967-06 Impact factor: 3.616

8. Association of protein fractions and lipids from human erythrocyte membranes. II. Studies on a loosely bound protein fraction.

Authors: D Schubert
Journal: Hoppe Seylers Z Physiol Chem Date: 1973-07

9. Maturation of the head of bacteriophage T4. I. DNA packaging events.

Authors: U K Laemmli; M Favre
Journal: J Mol Biol Date: 1973-11-15 Impact factor: 5.469

10. Ribosome-membrane interaction. Nondestructive disassembly of rat liver rough microsomes into ribosomal and membranous components.

Authors: M R Adelman; D D Sabatini; G Blobel
Journal: J Cell Biol Date: 1973-01 Impact factor: 10.539

28 in total

Association of poliovirus proteins with the endoplasmic reticulum.

1. In vitro assembly of polioviruses. 3. Assembly of 14 S particles into empty capsids by poliovirus-infected HeLa cell membranes.

2. Proteins associated with the poliovirus RNA replication complex.

3. Chemical and enzymatic characteristics of cytoplasmic membranes of poliovirus-infected HeLa cells.

4. Comparison of polysomal structures of uninfected and poliovirus infected HeLa cells.

5. Characterization of poliovirus-specific structures associated with cytoplasmic membranes.

6. The role of cytoplasmic membranes in poliovirus biosynthesis.

7. Cytopathology of Mengovirus infection. II. Proliferation of membranous cisternae.

8. Association of protein fractions and lipids from human erythrocyte membranes. II. Studies on a loosely bound protein fraction.

9. Maturation of the head of bacteriophage T4. I. DNA packaging events.

10. Ribosome-membrane interaction. Nondestructive disassembly of rat liver rough microsomes into ribosomal and membranous components.

1. cis-acting lesions targeted to the hydrophobic domain of a poliovirus membrane protein involved in RNA replication.

2. Poliovirus 2C region functions during encapsidation of viral RNA.

3. An authentic 3' noncoding region is necessary for efficient poliovirus replication.

4. Rescue of defective poliovirus RNA replication by 3AB-containing precursor polyproteins.

5. Replication-competent picornaviruses with complete genomic RNA 3' noncoding region deletions.

6. The effect of mengovirus infection on lipid synthesis in cultured Ehrlich ascites tumor cells.

7. Initiation of poliovirus plus-strand RNA synthesis in a membrane complex of infected HeLa cells.

8. Purification and partial characterization of poliovirus protease 2A by means of a functional assay.

9. Poliovirus 2C protein determinants of membrane binding and rearrangements in mammalian cells.

10. Effects of temperature and lipophilic agents on poliovirus formation and RNA synthesis in a cell-free system.