Literature DB >> 6091898

Termination of transcription in the mouse alpha-amylase gene Amy-2a occurs at multiple sites downstream of the polyadenylation site.

O Hagenbüchle, P K Wellauer, D L Cribbs, U Schibler.   

Abstract

We have delimited the region of transcription termination in the alpha-amylase gene Amy-2a. Mapping of in vitro elongated nascent transcripts to Amy-2a restriction fragments indicates that transcription terminates in a region between 2.5 and 4 kb downstream of the polyadenylation site. These runoff transcription experiments, combined with S1 nuclease mapping of nuclear transcripts at steady state, suggest that transcription termination occurs at multiple sites.

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Year:  1984        PMID： 6091898     DOI： 10.1016/0092-8674(84)90269-1

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  60 in total

1.  Termination of transcription in an 'in vitro' system is dependent on a polyadenylation sequence.

Authors:  V J Miralles
Journal:  Nucleic Acids Res       Date:  1991-07-11       Impact factor: 16.971

2.  Cell-type-specific synthesis of murine immunoglobulin mu RNA from an adenovirus vector.

Authors:  J E Ruether; A Maderious; D Lavery; J Logan; S M Fu; S Chen-Kiang
Journal:  Mol Cell Biol       Date:  1986-01       Impact factor: 4.272

3.  Sequence requirements for premature transcription arrest within the first intron of the mouse c-fos gene.

Authors:  N Mechti; M Piechaczyk; J M Blanchard; P Jeanteur; B Lebleu
Journal:  Mol Cell Biol       Date:  1991-05       Impact factor: 4.272

4.  A 78-kilobase region of mouse chromosome 3 contains salivary and pancreatic amylase genes and a pseudogene.

Authors:  K Wiebauer; D L Gumucio; J M Jones; R M Caldwell; H T Hartle; M H Meisler
Journal:  Proc Natl Acad Sci U S A       Date:  1985-08       Impact factor: 11.205

5.  The repressor sequence upstream of c-mos acts neither as polyadenylation site nor as transcription termination region.

Authors:  F A van der Hoorn; B Neupert
Journal:  Nucleic Acids Res       Date:  1986-11-25       Impact factor: 16.971

6.  RNA polymerase II transcription terminates at a specific DNA sequence in a HeLa cell-free reaction.

Authors:  K H Baek; K Sato; R Ito; K Agarwal
Journal:  Proc Natl Acad Sci U S A       Date:  1986-10       Impact factor: 11.205

7.  The DNA-binding activity of transcription factor PTF1 parallels the synthesis of pancreas-specific mRNAs during mouse development.

Authors:  S Petrucco; P K Wellauer; O Hagenbüchle
Journal:  Mol Cell Biol       Date:  1990-01       Impact factor: 4.272

8.  An intact histone 3'-processing site is required for transcription termination in a mouse histone H2a gene.

Authors:  N Chodchoy; N B Pandey; W F Marzluff
Journal:  Mol Cell Biol       Date:  1991-01       Impact factor: 4.272

9.  3' RNA processing efficiency plays a primary role in generating termination-competent RNA polymerase II elongation complexes.

Authors:  G Edwalds-Gilbert; J Prescott; E Falck-Pedersen
Journal:  Mol Cell Biol       Date:  1993-06       Impact factor: 4.272

10.  Polyadenylation and transcription termination in gene constructs containing multiple tandem polyadenylation signals.

Authors:  D B Batt; Y Luo; G G Carmichael
Journal:  Nucleic Acids Res       Date:  1994-07-25       Impact factor: 16.971
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