Literature DB >> 6091331

Characterization of murine hepatitis virus (JHM) RNA from rats with experimental encephalomyelitis.

D P Jackson, D H Percy, V L Morris.   

Abstract

When Wistar Furth rats are inoculated intracerebrally with the murine hepatitis virus JHM they often develop a demyelinating disease with resulting hind leg paralysis. Using an RNA transfer procedure and hybridization kinetic analysis, the virus-specific RNA in these rats was characterized. The pattern of JHM-specific RNA varied with individual infections of Wistar Furth rats. However, two species of JHM-specific RNA, the nucleocapsid and a 2.1-2.4 X 10(6)-Da RNA species were generally present. A general decrease in JHM-specific RNA in brains and spinal cord samples taken later than 20 days postinoculation was observed; however, JHM-specific RNA persisted in the spinal cord longer than in the brain of these rats.

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Year:  1984        PMID： 6091331      PMCID： PMC7131065          DOI： 10.1016/0042-6822(84)90221-6

Source DB:  PubMed          Journal:  Virology        ISSN： 0042-6822            Impact factor:   3.616


  14 in total

1.  Corona virus induced subacute demyelinating encephalomyelitis in rats: a morphological analysis.

Authors:  K Nagashima; H Wege; R Meyermann; V ter Meulen
Journal:  Acta Neuropathol       Date:  1978-10-13       Impact factor: 17.088

2.  Sequence relationships between the genome and the intracellular RNA species 1, 3, 6, and 7 of mouse hepatitis virus strain A59.

Authors:  W J Spaan; P J Rottier; M C Horzinek; B A van der Zeijst
Journal:  J Virol       Date:  1982-05       Impact factor: 5.103

3.  Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange.

Authors:  G K McMaster; G G Carmichael
Journal:  Proc Natl Acad Sci U S A       Date:  1977-11       Impact factor: 11.205

4.  Kinetic complexity of RNA molecules.

Authors:  M L Birnstiel; B H Sells; I F Purdom
Journal:  J Mol Biol       Date:  1972-01-14       Impact factor: 5.469

5.  Intracellular murine hepatitis virus-specific RNAs contain common sequences.

Authors:  S Cheley; R Anderson; M J Cupples; E C Chan; V L Morris
Journal:  Virology       Date:  1981-07-30       Impact factor: 3.616

6.  In vivo and in vitro models of demyelinating diseases. III. JHM virus infection of rats.

Authors:  O Sorensen; D Perry; S Dales
Journal:  Arch Neurol       Date:  1980-08

7.  Mouse hepatitis virus A59: mRNA structure and genetic localization of the sequence divergence from hepatotropic strain MHV-3.

Authors:  M M Lai; P R Brayton; R C Armen; C D Patton; C Pugh; S A Stohlman
Journal:  J Virol       Date:  1981-09       Impact factor: 5.103

8.  Genetic heterogeneity of murine coronaviruses.

Authors:  M M Lai; J O Fleming; S A Stohlman; K Fujiwara
Journal:  Arch Virol       Date:  1983       Impact factor: 2.574

9.  The virus-specific intracellular RNA species of two murine coronaviruses: MHV-a59 and MHV-JHM.

Authors:  J L Leibowitz; K C Wilhelmsen; C W Bond
Journal:  Virology       Date:  1981-10-15       Impact factor: 3.616

10.  Cell tropism and expression of mouse hepatitis viruses (MHV) in mouse spinal cord cultures.

Authors:  M E Dubois-Dalcq; E W Doller; M V Haspel; K V Holmes
Journal:  Virology       Date:  1982-06       Impact factor: 3.616
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  8 in total

1.  Pathogenicity of antigenic variants of murine coronavirus JHM selected with monoclonal antibodies.

Authors:  J O Fleming; M D Trousdale; F A el-Zaatari; S A Stohlman; L P Weiner
Journal:  J Virol       Date:  1986-06       Impact factor: 5.103

2.  Characterization of a variant virus selected in rat brains after infection by coronavirus mouse hepatitis virus JHM.

Authors:  F Taguchi; S G Siddell; H Wege; V ter Meulen
Journal:  J Virol       Date:  1985-05       Impact factor: 5.103

3.  Evolution of mouse hepatitis virus: detection and characterization of spike deletion variants during persistent infection.

Authors:  C L Rowe; S C Baker; M J Nathan; J O Fleming
Journal:  J Virol       Date:  1997-04       Impact factor: 5.103

4.  Replication of sialodacryoadenitis virus in mouse L-2 cells.

Authors:  D Percy; S Bond; J MacInnes
Journal:  Arch Virol       Date:  1989       Impact factor: 2.574

5.  Tumor progression and metastasis in murine D2 hyperplastic alveolar nodule mammary tumor cell lines.

Authors:  V L Morris; A B Tuck; S M Wilson; D Percy; A F Chambers
Journal:  Clin Exp Metastasis       Date:  1993-01       Impact factor: 5.150

6.  Characterization of coronavirus JHM variants isolated from Wistar Furth rats with a viral-induced demyelinating disease.

Authors:  V L Morris; C Tieszer; J Mackinnon; D Percy
Journal:  Virology       Date:  1989-03       Impact factor: 3.616

7.  Persistence and evolution of feline coronavirus in a closed cat-breeding colony.

Authors:  A A Herrewegh; M Mähler; H J Hedrich; B L Haagmans; H F Egberink; M C Horzinek; P J Rottier; R J de Groot
Journal:  Virology       Date:  1997-08-04       Impact factor: 3.616

8.  Late onset, symptomatic, demyelinating encephalomyelitis in mice infected with MHV-JHM in the presence of maternal antibody.

Authors:  S Perlman; R Schelper; E Bolger; D Ries
Journal:  Microb Pathog       Date:  1987-03       Impact factor: 3.738
  8 in total

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