Literature DB >> 6090933

Apparent discontinuous transcription of Trypanosoma brucei variant surface antigen genes.

D A Campbell, D A Thornton, J C Boothroyd.   

Abstract

The repeated mini-exon sequence that encodes the first 35 base pairs of all variant surface antigen mRNAs of Trypanosoma brucei directs the synthesis of a discrete 137-nucleotide transcript. It thus seems that variant surface antigen mRNAs are transcribed discontinuously, and we present two alternative models for how this might occur.

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Year:  1984        PMID： 6090933      PMCID： PMC7095118          DOI： 10.1038/311350a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  41 in total

1.  Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.

Authors:  P W Rigby; M Dieckmann; C Rhodes; P Berg
Journal:  J Mol Biol       Date:  1977-06-15       Impact factor: 5.469

2.  Activation of trypanosome surface glycoprotein genes involves a duplication-transposition leading to an altered 3' end.

Authors:  A Bernards; L H Van der Ploeg; A C Frasch; P Borst; J C Boothroyd; S Coleman; G A Cross
Journal:  Cell       Date:  1981-12       Impact factor: 41.582

Review 3.  The gene structure and replication of influenza virus.

Authors:  R A Lamb; P W Choppin
Journal:  Annu Rev Biochem       Date:  1983       Impact factor: 23.643

4.  The 5'-limit of transposition and upstream barren region of a trypanosome VSG gene: tandem 76 base-pair repeats flanking (TAA)90.

Authors:  D A Campbell; M P van Bree; J C Boothroyd
Journal:  Nucleic Acids Res       Date:  1984-03-26       Impact factor: 16.971

Review 5.  The control of variant surface antigen synthesis in trypanosomes.

Authors:  P Borst; A Bernards; L H van der Ploeg; P A Michels; A Y Liu; T de Lange; J M Kooter
Journal:  Eur J Biochem       Date:  1983-12-15

6.  6.5 S RNA; preliminary characterisation of unusual small RNAs in Trypanosoma brucei.

Authors:  J S Cordingley; M J Turner
Journal:  Mol Biochem Parasitol       Date:  1980-04       Impact factor: 1.759

7.  Sequences homologous to variant antigen mRNA spliced leader in Trypanosomatidae which do not undergo antigenic variation.

Authors:  R G Nelson; M Parsons; M Selkirk; G Newport; P J Barr; N Agabian
Journal:  Nature       Date:  1984 Apr 12-18       Impact factor: 49.962

8.  A U4-like small nuclear RNA is dispensable in yeast.

Authors:  D Tollervey; J A Wise; C Guthrie
Journal:  Cell       Date:  1983-12       Impact factor: 41.582

9.  Sequences homologous to the variant antigen mRNA spliced leader are located in tandem repeats and variable orphons in trypanosoma brucei.

Authors:  R G Nelson; M Parsons; P J Barr; K Stuart; M Selkirk; N Agabian
Journal:  Cell       Date:  1983-10       Impact factor: 41.582

10.  Repetitive DNA sequences cotranscribed with developmentally regulated Dictyostelium discoideum mRNAs.

Authors:  C Zuker; H F Lodish
Journal:  Proc Natl Acad Sci U S A       Date:  1981-09       Impact factor: 11.205
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  75 in total

1.  mRNA 5'-leader trans-splicing in the chordates.

Authors:  A E Vandenberghe; T H Meedel; K E Hastings
Journal:  Genes Dev       Date:  2001-02-01       Impact factor: 11.361

2.  Selective importation of RNA into isolated mitochondria from Leishmania tarentolae.

Authors:  M A Rubio; X Liu; H Yuzawa; J D Alfonzo; L Simpson
Journal:  RNA       Date:  2000-07       Impact factor: 4.942

Review 3.  trans and cis splicing in trypanosomatids: mechanism, factors, and regulation.

Authors:  Xue-hai Liang; Asaf Haritan; Shai Uliel; Shulamit Michaeli
Journal:  Eukaryot Cell       Date:  2003-10

Review 4.  mRNA processing in the Trypanosomatidae.

Authors:  K Perry; N Agabian
Journal:  Experientia       Date:  1991-02-15

5.  Characterization of VSG gene expression site promoters and promoter-associated DNA rearrangement events.

Authors:  K Gottesdiener; H M Chung; S D Brown; M G Lee; L H Van der Ploeg
Journal:  Mol Cell Biol       Date:  1991-05       Impact factor: 4.272

6.  Maturation of polycistronic pre-mRNA in Trypanosoma brucei: analysis of trans splicing and poly(A) addition at nascent RNA transcripts from the hsp70 locus.

Authors:  J Huang; L H van der Ploeg
Journal:  Mol Cell Biol       Date:  1991-06       Impact factor: 4.272

7.  Nucleotide sequence of the Leishmania donovani medRNA gene.

Authors:  K Wilson; S Hanson; S Landfear; B Ullman
Journal:  Nucleic Acids Res       Date:  1991-10-25       Impact factor: 16.971

8.  Apparent generation of a segmented mRNA from two separate tandem gene families in Trypanosoma cruzi.

Authors:  A Gonzalez; T J Lerner; M Huecas; B Sosa-Pineda; N Nogueira; P M Lizardi
Journal:  Nucleic Acids Res       Date:  1985-08-26       Impact factor: 16.971

9.  Incidence and changing patterns of uveitis in Central Tokyo.

Authors:  Takafumi Suzuki; Toshikatsu Kaburaki; Rie Tanaka; Shintaro Shirahama; Keiko Komae; Hisae Nakahara; Mitsuko Takamoto; Hidetoshi Kawashima; Makoto Aihara
Journal:  Int Ophthalmol       Date:  2021-05-28       Impact factor: 2.031

10.  Kinetoplastid RNA-editing-associated protein 1 (REAP-1): a novel editing complex protein with repetitive domains.

Authors:  S Madison-Antenucci; R S Sabatini; V W Pollard; S L Hajduk
Journal:  EMBO J       Date:  1998-11-02       Impact factor: 11.598
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