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Literature DB >> 6090218

Modelling the ATP-binding site of oncogene products, the epidermal growth factor receptor and related proteins.

Abstract

A three-dimensional model for the ATP-binding site of the oncogene product v-src is proposed by the use of interactive computer graphics. A similar model would apply to sequence related proteins such as other oncogene products, the epidermal growth factor receptor, cAMP-dependent protein kinase and the cell division control protein CDC28. The model was proposed on the basis of the conservation of certain key residues between the oncogene product family of proteins and several nucleotide binding proteins of known structures.

Entities: Chemical Gene

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Year: 1984 PMID： 6090218 DOI： 10.1016/0014-5793(84)80774-7

Source DB: PubMed Journal: FEBS Lett ISSN： 0014-5793 Impact factor: 4.124

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Cited

22 in total

1. Herpesviruses encode an unusual protein-serine/threonine kinase which is nonessential for growth in cultured cells.

Authors: N de Wind; J Domen; A Berns
Journal: J Virol Date: 1992-09 Impact factor: 5.103

2. Acetyl-CoA carboxylase from Escherichia coli: gene organization and nucleotide sequence of the biotin carboxylase subunit.

Authors: H Kondo; K Shiratsuchi; T Yoshimoto; T Masuda; A Kitazono; D Tsuru; M Anai; M Sekiguchi; T Tanabe
Journal: Proc Natl Acad Sci U S A Date: 1991-11-01 Impact factor: 11.205

3. The cloning and nucleotide sequence of cDNA for an amplified glutamine synthetase gene from the Chinese hamster.

Authors: B E Hayward; A Hussain; R H Wilson; A Lyons; V Woodcock; B McIntosh; T J Harris
Journal: Nucleic Acids Res Date: 1986-01-24 Impact factor: 16.971

4. Nucleotide sequence of the tail sheath gene of bacteriophage T4 and amino acid sequence of its product.

Authors: F Arisaka; T Nakako; H Takahashi; S Ishii
Journal: J Virol Date: 1988-04 Impact factor: 5.103

5. PHO85, a negative regulator of the PHO system, is a homolog of the protein kinase gene, CDC28, of Saccharomyces cerevisiae.

Authors: A Toh-e; K Tanaka; Y Uesono; R B Wickner
Journal: Mol Gen Genet Date: 1988-09

10. Isolation of temperature-sensitive mutations of the tyrosine kinase receptor sevenless (sev) in Drosophila and their use in determining its time of action.

Authors: M C Mullins; G M Rubin
Journal: Proc Natl Acad Sci U S A Date: 1991-11-01 Impact factor: 11.205

Modelling the ATP-binding site of oncogene products, the epidermal growth factor receptor and related proteins.

1. Herpesviruses encode an unusual protein-serine/threonine kinase which is nonessential for growth in cultured cells.

2. Acetyl-CoA carboxylase from Escherichia coli: gene organization and nucleotide sequence of the biotin carboxylase subunit.

3. The cloning and nucleotide sequence of cDNA for an amplified glutamine synthetase gene from the Chinese hamster.

4. Nucleotide sequence of the tail sheath gene of bacteriophage T4 and amino acid sequence of its product.

5. PHO85, a negative regulator of the PHO system, is a homolog of the protein kinase gene, CDC28, of Saccharomyces cerevisiae.

6. Adipose pyruvate carboxylase: amino acid sequence and domain structure deduced from cDNA sequencing.

7. Classification of doubly wound nucleotide binding topologies using automated loop searches.

8. Molecular cloning, characterization, and elicitation of acetyl-CoA carboxylase from alfalfa.

9. Structure and expression of STK, a src-related gene in the simple metazoan Hydra attenuata.

10. Isolation of temperature-sensitive mutations of the tyrosine kinase receptor sevenless (sev) in Drosophila and their use in determining its time of action.