Literature DB >> 6090170

Progesterone and estrogens in rat brain: modulation of GABA (gamma-aminobutyric acid) receptor activity.

A Maggi, J Perez.   

Abstract

Our data indicate that estrogens and progesterone can regulate the number of GABA receptors (as detected by [3H]muscimol binding assay) in rat brain. Both hormones act in selected areas. The extent of the effect (up to 160% increase) and the number of areas responsive suggest that sex hormones may play a very important role in the regulation of the functions of GABAergic transmission in the central nervous system.

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Year:  1984        PMID： 6090170     DOI： 10.1016/0014-2999(84)90205-x

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  16 in total

Review 1.  Psychotropic properties of ovarian estrogens (review).

Authors:  E B Arushanyan; G K Borovkova
Journal:  Neurosci Behav Physiol       Date:  1989 Jan-Feb

2.  Sex differences in GABAA receptor binding in rat brain measured by an improved in vitro binding assay.

Authors:  M Jüptner; C Hiemke
Journal:  Exp Brain Res       Date:  1990       Impact factor: 1.972

Review 3.  Olfaction, GABAergic neurotransmission in the olfactory bulb, and intermale aggression in mice: modulation by steroids.

Authors:  P V Guillot; G Chapouthier
Journal:  Behav Genet       Date:  1996-09       Impact factor: 2.805

4.  Estrogen augments hypothalamicβ-endorphin secretion and activates an inhibitoryβ-endorphin short-loop feedback system.

Authors:  S A Frautschy; D K Sarkar
Journal:  Endocrine       Date:  1995-04       Impact factor: 3.633

5.  GABA[A] receptor level changes in female hamster forebrain following in vivo estrogen progesterone and benzodiazepine treatment: a quantitative autoradiography analysis.

Authors:  M Canonaco; L H O'Connor; D W Pfaff; B S McEwen
Journal:  Exp Brain Res       Date:  1989       Impact factor: 1.972

6.  Estradiol and testosterone modulate the anesthetic action of the GABA-A agonist THIP, but not of the neurosteroid 3alpha,5beta-pregnanolone in the rat.

Authors:  Oscar González-Flores; Norma Sánchez; Marcos García-Juárez; Francisco Javier Lima-Hernández; Gabriela González-Mariscal; Carlos Beyer
Journal:  Psychopharmacology (Berl)       Date:  2003-12-17       Impact factor: 4.530

7.  Sex differences in diazepam effects and parvalbumin-positive GABA neurons in trait anxiety Long Evans rats.

Authors:  Rebecca Ravenelle; Nichole M Neugebauer; Timothy Niedzielak; S Tiffany Donaldson
Journal:  Behav Brain Res       Date:  2014-05-06       Impact factor: 3.332

8.  Activity of protein kinase C is important for 3alpha,5alpha-THP's actions at dopamine type 1-like and/or GABAA receptors in the ventral tegmental area for lordosis of rats.

Authors:  Cheryl A Frye; Alicia A Walf
Journal:  Brain Res Bull       Date:  2008-07-31       Impact factor: 4.077

9.  Are neuroactive steroids promising therapeutic agents in the management of acute and chronic pain?

Authors:  Vesna Jevtovic-Todorovic; Douglas F Covey; Slobodan M Todorovic
Journal:  Psychoneuroendocrinology       Date:  2009-12       Impact factor: 4.905

10.  Potentiation of the depression by adenosine of rat cerebral cortical neurones by progestational agents.

Authors:  J W Phillis
Journal:  Br J Pharmacol       Date:  1986-12       Impact factor: 8.739
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