Literature DB >> 6089909

Pool sizes of precursors for phosphatidylcholine formation in adult rat lung type II cells.

M Post, J J Batenburg, B T Smith, L M Van Golde.   

Abstract

The pool sizes of the choline intermediates and cofactors involved in the CDPcholine pathway were studied in alveolar type II cells from adult rat lung. The choline phosphate pool was much larger than both the choline and CDPcholine pools. Kinetic analysis of the pool sizes revealed that cholinephosphate cytidylyltransferase catalyzes a non-equilibrium reaction. These results are consistent with the idea that cholinephosphate cytidylyltransferase regulates the choline flux into phosphatidylcholine in adult rat lung type II cells.

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Year:  1984        PMID： 6089909     DOI： 10.1016/0005-2760(84)90185-1

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  9 in total

1.  Very low density lipoproteins stimulate surfactant lipid synthesis in vitro.

Authors:  R K Mallampalli; R G Salome; S L Bowen; D A Chappell
Journal:  J Clin Invest       Date:  1997-04-15       Impact factor: 14.808

2.  Betamethasone modulation of sphingomyelin hydrolysis up-regulates CTP:cholinephosphate cytidylyltransferase activity in adult rat lung.

Authors:  R K Mallampalli; S N Mathur; L J Warnock; R G Salome; G W Hunninghake; F J Field
Journal:  Biochem J       Date:  1996-08-15       Impact factor: 3.857

3.  Maternal administration of dexamethasone stimulates choline-phosphate cytidylyltransferase in fetal type II cells.

Authors:  M Post
Journal:  Biochem J       Date:  1987-01-01       Impact factor: 3.857

4.  Regulation of CTP: phosphocholine cytidylyltransferase activity in type II pneumonocytes.

Authors:  M Tesan; M M Anceschi; J E Bleasdale
Journal:  Biochem J       Date:  1985-12-15       Impact factor: 3.857

5.  Cytidine monophosphate-dependent synthesis of phosphatidylglycerol in permeabilized type II pneumonocytes.

Authors:  J E Bleasdale; N R Thakur; G R Rader; M Tesan
Journal:  Biochem J       Date:  1985-12-01       Impact factor: 3.857

6.  Stimulation of surfactant phospholipid biosynthesis in the lungs of rats treated with silica.

Authors:  B E Miller; G E Hook
Journal:  Biochem J       Date:  1988-08-01       Impact factor: 3.857

7.  Fatty acids stimulate phosphatidylcholine synthesis and CTP:choline-phosphate cytidylyltransferase in type II pneumocytes isolated from adult rat lung.

Authors:  R Burkhardt; P Von Wichert; J J Batenburg; L M Van Golde
Journal:  Biochem J       Date:  1988-09-01       Impact factor: 3.857

8.  Modulation of phosphatidylcholine biosynthesis by peroxisome proliferating fatty acid analogues.

Authors:  J Skorve; A M Svardal; M A Mansoor; R K Berge
Journal:  Lipids       Date:  1993-09       Impact factor: 1.880

9.  Alkalosis- and ATP-induced increases in the diacyglycerol pool in alveolar type II cells are derived from phosphatidylcholine and phosphatidylinositol.

Authors:  N Sen; A Chander
Journal:  Biochem J       Date:  1994-03-15       Impact factor: 3.857
  9 in total

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