Literature DB >> 6089790

1,25-Dihydroxyvitamin D3 inhibits selectively the mitogenic stimulation of mouse medullary thymocytes.

A Ravid, R Koren, A Novogrodsky, U A Liberman.   

Abstract

Mouse thymocytes were separated into cortical and medullary subpopulations by differential agglutination with peanut agglutinin. A high-affinity receptor for 1,25-dihydroxyvitamin D3 is present in medullary immunocompetent mouse thymocytes and is absent from cortical immature cells. 1,25-dihydroxyvitamin D3, at physiological concentrations, inhibits the mitogenic response of the medullary cells to phytohemagglutinin and interleukin-2, but has no effect on the cortical subpopulation. Other less active metabolites of vitamin D had little or no effect on medullary cell stimulation.

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Year:  1984        PMID： 6089790     DOI： 10.1016/0006-291x(84)90394-2

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  8 in total

1.  A computerized histomorphometric study of the effects of intoxication with vitamin D3 or 1,25 (OH)2D3 on growth and dentin production of impeded and unimpeded rat incisors.

Authors:  M Weinreb; M Weinreb
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1986

2.  1,25-Dihydroxyvitamin D3-mediated inhibition of human B cell differentiation.

Authors:  W C Chen; B Vayuvegula; S Gupta
Journal:  Clin Exp Immunol       Date:  1987-09       Impact factor: 4.330

3.  A phase I study of the vitamin D3 analogue ILX23-7553 administered orally to patients with advanced solid tumors.

Authors:  Rajul K Jain; Donald L Trump; Merrill J Egorin; Manuel Fernandez; Candace S Johnson; Ramesh K Ramanathan
Journal:  Invest New Drugs       Date:  2010-07-27       Impact factor: 3.850

4.  Distribution of the 1,25 dihydroxy-vitamin D3 receptor in the bursa of Fabricius of chicken.

Authors:  M Petrini; F Bianchi; A Dolfi; M Lupetti
Journal:  Experientia       Date:  1991-08-15

Review 5.  Light, vitamin D and psychiatry. Role of 1,25 dihydroxyvitamin D3 (soltriol) in etiology and therapy of seasonal affective disorder and other mental processes.

Authors:  W E Stumpf; T H Privette
Journal:  Psychopharmacology (Berl)       Date:  1989       Impact factor: 4.530

6.  Defective binding and function of 1,25-dihydroxyvitamin D3 receptors in peripheral mononuclear cells of patients with end-organ resistance to 1,25-dihydroxyvitamin D.

Authors:  R Koren; A Ravid; U A Liberman; Z Hochberg; Y Weisman; A Novogrodsky
Journal:  J Clin Invest       Date:  1985-11       Impact factor: 14.808

7.  Thymic Epithelial Cell Support of Thymopoiesis Does Not Require Klotho.

Authors:  Yan Xing; Michelle J Smith; Christine A Goetz; Ron T McElmurry; Sarah L Parker; Dullei Min; Georg A Hollander; Kenneth I Weinberg; Jakub Tolar; Heather E Stefanski; Bruce R Blazar
Journal:  J Immunol       Date:  2018-10-29       Impact factor: 5.422

Review 8.  Impact of vitamin D on immune function: lessons learned from genome-wide analysis.

Authors:  Rene F Chun; Philip T Liu; Robert L Modlin; John S Adams; Martin Hewison
Journal:  Front Physiol       Date:  2014-04-21       Impact factor: 4.566
  8 in total

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