Literature DB >> 6089661

Enzymatic synthesis of flavin adenine dinucleotide.

S Shimizu, K Yamane, Y Tani, H Yamada.   

Abstract

A new and simple enzymatic method for the synthesis of flavin adenine dinucleotide (FAD) from flavin mononucleotide by the transadenylylation reaction using microbial cells is described. Among various microorganisms tested, Artherobacter globiformis IFO 12138 and two soil bacteria were selected as useful enzyme sources. Under suitable reaction conditions, the amount of FAD synthesized was 2.25 mumol/mL with cells of A. globiformis. The transadenylylation reaction could be coupled with the ATP supplying system through a glycolysis process with yeast.

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Year:  1983        PMID： 6089661     DOI： 10.1007/bf02778261

Source DB:  PubMed          Journal:  Appl Biochem Biotechnol        ISSN： 0273-2289            Impact factor:   2.926


  4 in total

1.  SYNTHESIS OF NUCLEOTIDE ANHYDRIDES BY ANION EXCHANGE.

Authors:  A M MICHELSON
Journal:  Biochim Biophys Acta       Date:  1964-09-11

2.  The separation of flavins by paper electrophoresis and its application to the examination of the flavin contents of micro-organisms.

Authors:  J L PEEL
Journal:  Biochem J       Date:  1958-07       Impact factor: 3.857

3.  A new method for preparing flavin-adenine dinucleotide.

Authors:  L G WHITBY
Journal:  Biochem J       Date:  1953-06       Impact factor: 3.857

4.  Production of flavine-adenine dinucleotide from riboflavine by a mutant of Sarcina lutea.

Authors:  T Watanabe; T Uchida; J Kato; I Chibata
Journal:  Appl Microbiol       Date:  1974-03
  4 in total
  2 in total

Review 1.  Genetic control of biosynthesis and transport of riboflavin and flavin nucleotides and construction of robust biotechnological producers.

Authors:  Charles A Abbas; Andriy A Sibirny
Journal:  Microbiol Mol Biol Rev       Date:  2011-06       Impact factor: 11.056

2.  Metabolic and bioprocess engineering of the yeast Candida famata for FAD production.

Authors:  Valentyna Y Yatsyshyn; Dariya V Fedorovych; Andriy A Sibirny
Journal:  J Ind Microbiol Biotechnol       Date:  2014-03-05       Impact factor: 3.346
  2 in total

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