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Literature DB >> 6089343

Insulin-mediated regulation of neuronal maturation.

Abstract

Exposure to insulin increased stimulus-evoked transmission at synapses formed in culture by cholinergic retinal neurons derived from fetal rats. This effect occurred at physiological concentrations and was long lasting. The findings support the hypothesis that insulin may serve as a developmental signal to regulate the emergence of effective neurotransmission across nascent synapses.

Entities: Species

Mesh：

Substances：
Insulin

Year: 1984 PMID： 6089343 DOI： 10.1126/science.6089343

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

32 in total

1. Differential expression of four genes encoding molluscan insulin-related peptides in the central nervous system of the pond snail Lymnaea stagnalis.

Authors: I Meester; M D Ramkema; J van Minnen; H H Boer
Journal: Cell Tissue Res Date: 1992-07 Impact factor: 5.249

2. Evidence for entry of plasma insulin into cerebrospinal fluid through an intermediate compartment in dogs. Quantitative aspects and implications for transport.

Authors: M W Schwartz; R N Bergman; S E Kahn; G J Taborsky; L D Fisher; A J Sipols; S C Woods; G M Steil; D Porte
Journal: J Clin Invest Date: 1991-10 Impact factor: 14.808

Review 3. Metabolic imprinting: critical impact of the perinatal environment on the regulation of energy homeostasis.

Authors: Barry E Levin
Journal: Philos Trans R Soc Lond B Biol Sci Date: 2006-07-29 Impact factor: 6.237

Review 4. The early intracellular signaling pathway for the insulin/insulin-like growth factor receptor family in the mammalian central nervous system.

Authors: F Folli; S Ghidella; L Bonfanti; C R Kahn; A Merighi
Journal: Mol Neurobiol Date: 1996-10 Impact factor: 5.590

9. Insulin-like growth factor I receptors of fetal brain are enriched in nerve growth cones and contain a beta-subunit variant.

Authors: S Quiroga; R S Garofalo; K H Pfenninger
Journal: Proc Natl Acad Sci U S A Date: 1995-05-09 Impact factor: 11.205

Review 10. Interaction of perinatal and pre-pubertal factors with genetic predisposition in the development of neural pathways involved in the regulation of energy homeostasis.

Authors: Barry E Levin
Journal: Brain Res Date: 2010-01-06 Impact factor: 3.252

Insulin-mediated regulation of neuronal maturation.

1. Differential expression of four genes encoding molluscan insulin-related peptides in the central nervous system of the pond snail Lymnaea stagnalis.

2. Evidence for entry of plasma insulin into cerebrospinal fluid through an intermediate compartment in dogs. Quantitative aspects and implications for transport.

Review 3. Metabolic imprinting: critical impact of the perinatal environment on the regulation of energy homeostasis.

Review 4. The early intracellular signaling pathway for the insulin/insulin-like growth factor receptor family in the mammalian central nervous system.

Review 5. Insulin and insulin-like growth factor receptors in the nervous system.

6. Relationship of insulin-like growth factor II gene expression in muscle to synaptogenesis.

7. Insulin synthesis in chick embryo retinas during development.

8. Chick embryo retina development in vitro: the effect of insulin.

9. Insulin-like growth factor I receptors of fetal brain are enriched in nerve growth cones and contain a beta-subunit variant.

Review 10. Interaction of perinatal and pre-pubertal factors with genetic predisposition in the development of neural pathways involved in the regulation of energy homeostasis.