| Literature DB >> 6089248 |
M L Mavroidis, D R Kanter, D N Greenblum, D L Garver.
Abstract
alpha 2-Adrenergic receptor sensitivity was assessed during desipramine treatment by carefully monitoring clonidine-induced blood pressure changes, as well as symptomatology, in three patients with major depressive disorder. The data appear to be consistent with the hypothesis that the antidepressant action of desipramine is mediated by alpha 2-autoreceptor desensitization.Entities:
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Year: 1984 PMID： 6089248 DOI： 10.1007/bf00464799
Source DB: PubMed Journal: Psychopharmacology (Berl) ISSN： 0033-3158 Impact factor: 4.530