Literature DB >> 6088318

The effect of zinc on [59Fe]lactoferrin binding to blood neutrophilic leucocytes and colostral cells.

A I Maneva, V V Manev, L M Sirakov.   

Abstract

Zn2+ inhibits the binding of [59Fe]lactoferrin to neutrophilic leucocytes. The inhibiting effect is proportional to zinc concentration in the range 10-330 mumol/l. Zn2+ inhibits the [59Fe]lactoferrin binding to the colostral cells in the same degree as PMN. The inhibiting effect of Zn2+ on [59Fe]lactoferrin binding to neutrophilic leucocytes is equal to those of non-labelled lactoferrin and transferrin. Fe2+ and Cu2+ does not have such effect on binding of [59Fe]lactoferrin to the PMN leucocytes.

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Year:  1984        PMID: 6088318     DOI: 10.1016/0020-711x(84)90191-5

Source DB:  PubMed          Journal:  Int J Biochem        ISSN: 0020-711X


  1 in total

1.  Competition of Mn2+ and Zn2+ with 59Fe2+ and 59Fe3+ for the plasma membrane receptors from lactating mouse mammary gland.

Authors:  D A Moutafchiev; L M Sirakov
Journal:  Biol Trace Elem Res       Date:  1992-12       Impact factor: 3.738

  1 in total

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