Literature DB >> 608822

Experimental studies on factors causing acute serum sickness glomerulonephritis of immune complex origin. II. Pathomorphological analysis.

J Szabó, T Szabó, G Lustyik, A Lenkey.   

Abstract

Seventeen rabbits were given a single, large dose of bovine serum albumin (BSA) intravenously. Percutaneous kidney biopsy was carried out on the 14th and 31st days after BSA administration. Proteinuria was measured and the glomerular changes were analysed in order to find a correlation between the degree of proteinuria and glomerular alterations, i.e. number of electron-dense deposits (EDD), polymorphonuclear leukocytes (PMNL), and mononuclear marcophages (MNM). The results speak in favour of the decisive role of mononuclear macrophages in enhancement of glomerular permeability.

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Year:  1977        PMID： 608822     DOI： 10.1007/bf02082174

Source DB:  PubMed          Journal:  Int Urol Nephrol        ISSN： 0301-1623            Impact factor:   2.370


  33 in total

1.  Pathogenesis of serum sickness.

Authors:  F J DIXON; J J VAZQUEZ; W O WEIGLE; C G COCHRANE
Journal:  AMA Arch Pathol       Date:  1958-01

2.  Acute focal glomerulonephritis in the rabbit induced by injection of Saccharomyces cerevisiae. An electron microscopic study.

Authors:  W H Johnston; H Latta
Journal:  Lab Invest       Date:  1972-06       Impact factor: 5.662

3.  Antigen quantitation in experimental immune complex glomerulonephritis. I. Acute serum sickness.

Authors:  C B Wilson; F J Dixon
Journal:  J Immunol       Date:  1970-08       Impact factor: 5.422

4.  Glomerular findings in mixed IgG-IgM cryoglobulinemia. Light, electron microscopic, immunofluorescence and histochemical correlations.

Authors:  G Monga; G Mazzucco; R Coppo; G Piccoli; R Coda
Journal:  Virchows Arch B Cell Pathol       Date:  1976-04-29

5.  The macrophagen in human rapidly progressive glomerulonephritis.

Authors:  R C Atkins; S R Holdsworth; E F Glasgow; F E Matthews
Journal:  Lancet       Date:  1976-04-17       Impact factor: 79.321

6.  Experimental glomerulonephritis. The pathogenesis of a laboratory model resembling the spectrum of human glomerulonephritis.

Authors:  F J DIXON; J D FELDMAN; J J VAZQUEZ
Journal:  J Exp Med       Date:  1961-05-01       Impact factor: 14.307

7.  Electron microscopy of serum sickness nephritis.

Authors:  J D FELDMAN
Journal:  J Exp Med       Date:  1958-12-01       Impact factor: 14.307

8.  Quantitation of acute and chronic serum sickness in the rabbit.

Authors:  C B Wilson; F J Dixon
Journal:  J Exp Med       Date:  1971-09-01       Impact factor: 14.307

9.  Mechanisms involved in the deposition of immune complexes in tissues.

Authors:  C G Cochrane
Journal:  J Exp Med       Date:  1971-09-01       Impact factor: 14.307

10.  A ROLE OF POLYMORPHONUCLEAR LEUKOCYTES AND COMPLEMENT IN NEPHROTOXIC NEPHRITIS.

Authors:  C G COCHRANE; E R UNANUE; F J DIXON
Journal:  J Exp Med       Date:  1965-07-01       Impact factor: 14.307
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  2 in total

1.  Granulomatous glomerulonephritis, without systemic disorder.

Authors:  J Szabó; I Biró; T Tóth; I Worum; G Velok
Journal:  Virchows Arch A Pathol Anat Histol       Date:  1978-12-12

2.  Experimental glomerular lesions induced by chronic immune complex formation. II. Pathomorphological analysis.

Authors:  J Szabó; T Szabó; T Tóth; G Lustyik; C Balázs
Journal:  Int Urol Nephrol       Date:  1979       Impact factor: 2.370
  2 in total

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