Life stress as a precursor to adolescent drug dependence.

Though drug dependence is often characterized as a stress-produced disorder, there seems to be little or no quantitative data relating stress and drug dependence. In this study a recognized instrument for the measurement of stress, Coddington's Life Event Record, was administered to 31 drug-dependent adolescents by estimating levels of life stress during the year preceding their first illicit drug use. The drug-dependent subjects showed significantly higher life stress scores than did a standard normal population of adolescents. The null hypothesis of no difference was rejected at the .005 level. A stress-reduction theory of drug dependence gains support from these results.