Literature DB >> 6087456

Leukotriene B4 produces hyperalgesia that is dependent on polymorphonuclear leukocytes.

J D Levine, W Lau, G Kwiat, E J Goetzl.   

Abstract

Leukotriene B4, at the same intracutaneous doses as bradykinin, reduced the nociceptive threshold in the rat paw. The mechanism of leukotriene B4-induced hyperalgesia was distinguished from that of the hyperalgesia elicited by prostaglandin E2 and bradykinin by its dependence on polymorphonuclear leukocytes and independence of the cyclooxygenation of arachidonic acid.

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Year:  1984        PMID: 6087456     DOI: 10.1126/science.6087456

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  51 in total

1.  Phytochemical, analgesic and anti-inflammatory effects of the ethylacetate extract of the leaves of Pseudocedrella kotschyii.

Authors:  Y M Musa; A K Haruna; M Ilyas; A H Yaro; A A Ahmadu; H Usman
Journal:  Afr J Tradit Complement Altern Med       Date:  2007-10-27

2.  Antinociceptive and anti-inflammatory effects of a mucin-binding agglutinin isolated from the red marine alga Hypnea cervicornis.

Authors:  Flávio da S Bitencourt; Jozi G Figueiredo; Mário R L Mota; Carla C R Bezerra; Priscila P Silvestre; Marcus R Vale; Kyria S Nascimento; Alexandre H Sampaio; Celso S Nagano; Silvana Saker-Sampaio; Wladimir R L Farias; Benildo S Cavada; Ana M S Assreuy; Nylane M N de Alencar
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2008-02-13       Impact factor: 3.000

3.  Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances.

Authors:  S W Hwang; H Cho; J Kwak; S Y Lee; C J Kang; J Jung; S Cho; K H Min; Y G Suh; D Kim; U Oh
Journal:  Proc Natl Acad Sci U S A       Date:  2000-05-23       Impact factor: 11.205

4.  Role of a nonsteroidal anti-inflammatory agent, ibuprofen, in coronary revascularization after acute myocardial infarction.

Authors:  R Clement; D K Das; R M Engelman; H Otani; D Bandhyopadhyay; S Hoory; M Antar; J A Rousou; R H Breyer; M R Prasad
Journal:  Basic Res Cardiol       Date:  1990 Jan-Feb       Impact factor: 17.165

5.  Effect of a 5-lipoxygenase inhibitor and leukotriene antagonist (PF 5901) on antigen-induced airway responses in neonatally immunized rabbits.

Authors:  C M Herd; D Donigi-Gale; T S Shoupe; D A Burroughs; M Yeadon; C P Page
Journal:  Br J Pharmacol       Date:  1994-05       Impact factor: 8.739

6.  Identification of a B2 bradykinin receptor expressed by PC12 pheochromocytoma cells.

Authors:  J Nardone; C Gerald; L Rimawi; L Song; P G Hogan
Journal:  Proc Natl Acad Sci U S A       Date:  1994-05-10       Impact factor: 11.205

7.  Altered inflammatory responses in leukotriene-deficient mice.

Authors:  J L Goulet; J N Snouwaert; A M Latour; T M Coffman; B H Koller
Journal:  Proc Natl Acad Sci U S A       Date:  1994-12-20       Impact factor: 11.205

8.  Targeting endothelin ETA and ETB receptors inhibits antigen-induced neutrophil migration and mechanical hypernociception in mice.

Authors:  Waldiceu A Verri; Thiago M Cunha; Danilo A Magro; Ana T G Guerrero; Silvio M Vieira; Vanessa Carregaro; Guilherme R Souza; Maria das Graças M O Henriques; Sérgio H Ferreira; Fernando Q Cunha
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2008-10-15       Impact factor: 3.000

9.  Role of PAF receptor in proinflammatory cytokine expression in the dorsal root ganglion and tactile allodynia in a rodent model of neuropathic pain.

Authors:  Shigeo Hasegawa; Yuta Kohro; Miho Shiratori; Satoshi Ishii; Takao Shimizu; Makoto Tsuda; Kazuhide Inoue
Journal:  PLoS One       Date:  2010-05-03       Impact factor: 3.240

10.  Analgesic and Anti-Inflammatory Properties of Extracts from the Bulbils of Dioscorea bulbifera L. var sativa (Dioscoreaceae) in Mice and Rats.

Authors:  M Mbiantcha; A Kamanyi; R B Teponno; A L Tapondjou; P Watcho; T B Nguelefack
Journal:  Evid Based Complement Alternat Med       Date:  2010-09-08       Impact factor: 2.629

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