Literature DB >> 6087209

Benzodiazepine and GABA receptors in early Huntington's disease.

F O Walker, A B Young, J B Penney, K Dovorini-Zis, I Shoulson.   

Abstract

We compared autoradiographic measurements of GABA and benzodiazepine receptors in the brains of two early cases of Huntington's disease (HD), five controls, and four advanced cases of HD. These receptors increase in lateral globus pallidus and decrease in putamen early in the disease, before there is any extensive cell loss and atrophy. The cause of these receptor changes is unknown, but could imply dysfunction rather than death of striatal neurons.

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Year:  1984        PMID： 6087209     DOI： 10.1212/wnl.34.9.1237

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  10 in total

1.  From neuronal inclusions to neurodegeneration: neuropathological investigation of a transgenic mouse model of Huntington's disease.

Authors:  S W Davies; M Turmaine; B A Cozens; A S Raza; A Mahal; L Mangiarini; G P Bates
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1999-06-29       Impact factor: 6.237

Review 2.  Altered neurotransmitter receptor expression in transgenic mouse models of Huntington's disease.

Authors:  J H Cha; A S Frey; S A Alsdorf; J A Kerner; C M Kosinski; L Mangiarini; J B Penney; S W Davies; G P Bates; A B Young
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1999-06-29       Impact factor: 6.237

3.  Visualizing receptors for neurotransmitters in the human brain with autoradiography.

Authors:  J M Palacios; G Chinaglia; A Probst
Journal:  Neurosurg Rev       Date:  1989       Impact factor: 3.042

4.  Benzodiazepine receptor quantification in Huntington's disease with [(123)I]omazenil and SPECT.

Authors:  L H Pinborg; C Videbaek; S G Hasselbalch; S A Sørensen; A Wagner; O B Paulson; G M Knudsen
Journal:  J Neurol Neurosurg Psychiatry       Date:  2001-05       Impact factor: 10.154

Review 5.  Alteration of GABAergic neurotransmission in Huntington's disease.

Authors:  Maurice Garret; Zhuowei Du; Marine Chazalon; Yoon H Cho; Jérôme Baufreton
Journal:  CNS Neurosci Ther       Date:  2018-02-21       Impact factor: 5.243

Review 6.  Genetics and neuropathology of Huntington's disease.

Authors:  Anton Reiner; Ioannis Dragatsis; Paula Dietrich
Journal:  Int Rev Neurobiol       Date:  2011       Impact factor: 3.230

Review 7.  Disrupted striatal neuron inputs and outputs in Huntington's disease.

Authors:  Anton Reiner; Yun-Ping Deng
Journal:  CNS Neurosci Ther       Date:  2018-04       Impact factor: 5.243

8.  Differential loss of striatal projection neurons in Huntington disease.

Authors:  A Reiner; R L Albin; K D Anderson; C J D'Amato; J B Penney; A B Young
Journal:  Proc Natl Acad Sci U S A       Date:  1988-08       Impact factor: 11.205

Review 9.  Insights into GABAAergic system alteration in Huntington's disease.

Authors:  Yi-Ting Hsu; Ya-Gin Chang; Yijuang Chern
Journal:  Open Biol       Date:  2018-12-05       Impact factor: 6.411

Review 10.  Cellular basis of learning and memory in the carotid body.

Authors:  Olivia M S Gold; Emma N Bardsley; Anna P Ponnampalam; Audrys G Pauza; Julian F R Paton
Journal:  Front Synaptic Neurosci       Date:  2022-08-15
  10 in total

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