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Literature DB >> 608686

In vitro inhibition of human peripheral blood lymphocyte transformation by an extract of Pseudomonas putida.

C V Hunt, W Khan, G Friedman, J C Houck.

Abstract

An extract prepared from a psychrophilic strain of Pseudomonas putida was found to cause a dose-dependent inhibition of [H3]TdR incorporation into human peripheral blood lymphocytes stimulated with PHA, ConA, PWM, or in a mixed lymphocyte reaction. The inhibition was found not to be the result of cytotoxicity, culture medium depletion of a component necessary for lymphocyte transformation, or interference with label uptake by blast lymphocytes. The extract was most effective when added prior to 48 h of mitogen stimulation. The inhibitory material was photeolytic enzyme degradable, heat-stable and non-dialyzable.

Entities: Disease Species

Mesh：

Substances：

Year: 1977 PMID： 608686 PMCID： PMC1445343

Source DB: PubMed Journal: Immunology ISSN： 0019-2805 Impact factor: 7.397

15 in total

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4. The differential effect of cholera toxin on the lymphocyte stimulation induced by various mitogens.

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5. Pathophysiologic effects of lethal and immunoregulatory doses of cholera enterotoxin in the mouse.

Authors: F V Chisari; R S Northrup
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6. Lymphocyte transformation and macrophage migration inhibition by electrofocused and gel-filtered fractions of group A streptococcal filtrate.

Authors: E Seravalli; A Taranta
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1. In vitro lymphocyte stimulation in leprosy; simultaneous stimulation with Mycobacterium leprae antigens and phytohaemagglutinin.

Authors: G Bjune
Journal: Clin Exp Immunol Date: 1979-06 Impact factor: 4.330

2. Inhibition of lymphocyte growth by Ulex seed extracts (USE).

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2 in total

In vitro inhibition of human peripheral blood lymphocyte transformation by an extract of Pseudomonas putida.

1. A potent antimitogenic factor from group A streptococci.

2. PSYCHROPHILIC BACTERIA.

3. Modulation of in vivo antibody responses by cholera toxin.

4. The differential effect of cholera toxin on the lymphocyte stimulation induced by various mitogens.

5. Pathophysiologic effects of lethal and immunoregulatory doses of cholera enterotoxin in the mouse.

6. Lymphocyte transformation and macrophage migration inhibition by electrofocused and gel-filtered fractions of group A streptococcal filtrate.

7. The modulating effect of cholera enterotoxin on the immune response.

8. L-asparaginase and blastogenesis.

9. Inhibition of mitogen stimulation of human peripheral blood leukocytes by Vibrio cholerae enterotoxin.

10. Studies of PPLO infection. V. Inhibition of lymphocyte mitosis and antibody formation by mycoplasmal extracts.

1. In vitro lymphocyte stimulation in leprosy; simultaneous stimulation with Mycobacterium leprae antigens and phytohaemagglutinin.

2. Inhibition of lymphocyte growth by Ulex seed extracts (USE).