| Literature DB >> 6086596 |
K Hirai, K Ikuta, K Maotani, S Kato.
Abstract
Marek's disease virus (MDV) showed only 0.3-0.6% homology in DNA sequence with herpesvirus of turkeys (HVT) at Tm-24.4 degrees C in spite of its antigenic similarity to the latter. Southern blot hybridization under stringent conditions showed that the homology between MDV and HVT is located in the restricted portion of these viral genomes. At Tm-49.6 degrees C, which permits the detection of homology with one base mismatch in three between the MDV and HVT DNAs, sequences with weak homology were found to be distributed over most of these viral genomes. No homology was detected between Epstein-Barr virus and either MDV or HVT DNA.Entities:
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Year: 1984 PMID: 6086596 DOI: 10.1093/oxfordjournals.jbchem.a134712
Source DB: PubMed Journal: J Biochem ISSN: 0021-924X Impact factor: 3.387