Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Ly-1 inducer and Ly-1,2 acceptor T cells in the feedback suppression circuit bear an I-J-subregion controlled determinant.

Literature DB >> 6086090

Ly-1 inducer and Ly-1,2 acceptor T cells in the feedback suppression circuit bear an I-J-subregion controlled determinant.

D D Eardley¹, D B Murphy, J D Kemp, F W Shen, H Cantor, R K Gershon.

Abstract

An I-J-subregion controlled determinant is expressed on Ly-1 inducer and Ly-1,2 acceptor T cells in the feedback suppression circuit. Ly-1 T cells absorb the I-J antibody reactive with the Ly-1,2 acceptor T cell, suggesting that both inducer and acceptor T cells have the same I-J determinant. Since less than 10 percent of Ly-1 or Ly-1,2 T cells are killed by anti-I-J plus complement treatment, the I-J determinant demarcates functionally distinct subsets of both the Ly-1 and Ly-1,2 T-cell sets. This I-J determinant is not expressed on a detectable number of Ly-1 helper T cells which induce B lymphocytes to produce anti-sheep red cell antibody in tissue culture.

Entities: Species

Mesh：

Substances：

Year: 1980 PMID： 6086090 DOI： 10.1007/bf01567824

Source DB: PubMed Journal: Immunogenetics ISSN： 0093-7711 Impact factor: 2.846

13 in total

1. Immunoregulatory circuits among T cell sets: effect of mode of immunization on determining which Lyl T cell sets will be activated.

Authors: D D Eardley; J Kemp; F W Shen; H Cantor; R K Gershon
Journal: J Immunol Date: 1979-05 Impact factor: 5.422

2. The expression of Ia antigenic determinants on macrophages required for the in vitro antibody response.

Authors: J E Niederhuber; P Allen; L Mayo
Journal: J Immunol Date: 1979-04 Impact factor: 5.422

Review 3. Helper and suppressor T cell factors.

Authors: R N Germain; B Benacerraf
Journal: Springer Semin Immunopathol Date: 1980-05

4. In vivo or in vitro treatments with anti-I-J alloantisera abolish immunity to AKR leukemia.

Authors: D Meruelo; N Flieger; D Smith; H O McDevitt
Journal: Proc Natl Acad Sci U S A Date: 1980-04 Impact factor: 11.205

5. Immunoregulatory circuits among T-cell sets. Identification of a subpopulation of T-helper cells that induces feedback inhibition.

Authors: H Cantor; J Hugenberger; L McVay-Boudreau; D D Eardley; J Kemp; F W Shen; R K Gershon
Journal: J Exp Med Date: 1978-10-01 Impact factor: 14.307

6. A new I subregion (I-J) marked by a locus (Ia-4) controlling surface determinants on suppressor T lymphocytes.

Authors: D B Murphy; L A Herzenberg; K Okumura; L A Herzenberg; H O McDevitt
Journal: J Exp Med Date: 1976-09-01 Impact factor: 14.307

7. Genetic control of immunoregulatory circuits. Genes linked to the Ig locus govern communication between regulatory T-cell sets.

Authors: D D Eardley; F W Shen; H Cantor; R K Gershon
Journal: J Exp Med Date: 1979-07-01 Impact factor: 14.307

8. Two distinct types of helper T cells involved in the secondary antibody response: independent and synergistic effects of Ia- and Ia+ helper T cells.

Authors: T Tada; T Takemori; K Okumura; M Nonaka; T Tokuhisa
Journal: J Exp Med Date: 1978-02-01 Impact factor: 14.307

9. Intermediary role of macrophages in the passage of suppressor signals between T-cell subsets.

Authors: W Ptak; M Zembala; R K Gershon
Journal: J Exp Med Date: 1978-08-01 Impact factor: 14.307

10. Immunoregulatory circuits among T-cell sets. I. T-helper cells induce other T-cell sets to exert feedback inhibition.

Authors: D D Eardley; J Hugenberger; L McVay-Boudreau; F W Shen; R K Gershon; H Cantor
Journal: J Exp Med Date: 1978-04-01 Impact factor: 14.307

14 in total

Review 1. Antigen-specific suppressor factor: missing pieces in the puzzle.

Authors: R M O'Hara
Journal: Immunol Res Date: 1995 Impact factor: 2.829

2. Immunotherapy of experimental arthritis. Analysis of the articular cartilage of mice suppressed for collagen-induced arthritis by a T-cell hybridoma.

Authors: T F Kresina
Journal: Am J Pathol Date: 1987-11 Impact factor: 4.307

3. I-J-positive cloned macrophages as accessory cells for the induction of suppressor T cells in vitro.

Authors: R M Nakamura; Y Nakamura; A Nagayama; T Tokunaga
Journal: Immunol Res Date: 1986 Impact factor: 2.829

4. T cells in a suppressor circuit and non-T:non-B cells bear different I-J determinants.

Authors: D B Murphy; K Yamauchi; S Habu; D D Eardley; R K Gershon
Journal: Immunogenetics Date: 1981 Impact factor: 2.846

5. The role of I-J in the suppressor T-cell circuit which influences the effector stage of contact sensitivity: antigen together with syngeneic I-J region determinants induces and activates T suppressor cells.

Authors: V Colizzi; G L Asherson; B M James
Journal: Immunology Date: 1983-05 Impact factor: 7.397

Review 6. Special regulatory T cell review: The resurgence of the concept of contrasuppression in immunoregulation.

Authors: Thomas Lehner
Journal: Immunology Date: 2008-01 Impact factor: 7.397

7. Assessment of the diabetogenic drugs alloxan and streptozotocin as models for the study of immune defects in diabetic mice.

Authors: G N Gaulton; J L Schwartz; D D Eardley
Journal: Diabetologia Date: 1985-10 Impact factor: 10.122

8. Adoptive transfer of suppression of arthritis in the mouse model of collagen-induced arthritis. Evidence for a type II collagen-specific suppressor T cell.

Authors: T F Kresina; R W Moskowitz
Journal: J Clin Invest Date: 1985-06 Impact factor: 14.808

9. Generation of anti-NZB red blood cell antibody-forming plasma cells from bone marrow cultures of syngeneic and allogeneic mice: functional modulation of helper T-cell subsets in autosensitization.

Authors: K Nakamura; T Akahoshi; A Yoshii; S Kashiwazaki
Journal: Immunology Date: 1983-03 Impact factor: 7.397

10. Concomitant cellular and humoral expression of a regulatory cross-reactive idiotype in acute Schistosoma japonicum infection.

Authors: T F Kresina; G R Olds
Journal: Infect Immun Date: 1986-07 Impact factor: 3.441