Literature DB >> 6083472

Delayed-type hypersensitivity to myelin basic proteins in mice susceptible to allergic encephalomyelitis.

D S Linthicum, G A Hashim.   

Abstract

The delayed-type hypersensitivity (DTH) response in mice immunized with autologous spinal cord homogenate or purified myelin basic protein (MBP) was measured by the 125I-UdR uptake ear assay. Mice were tested for DTH responses with MBP preparations from different species and with synthetic peptides. The 114-122 and 68-84 peptide regions appear to be major determinants for inducing and eliciting DTH in the mice which are susceptible to allergic encephalomyelitis.

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Year:  1984        PMID： 6083472     DOI： 10.1007/bf00964673

Source DB:  PubMed          Journal:  Neurochem Res        ISSN： 0364-3190            Impact factor:   3.996


  26 in total

1.  Role of T lymphocytes in the pathogenesis of experimental autoimmune encephalomyelitis.

Authors:  V A Lennon; W J Byrd
Journal:  Eur J Immunol       Date:  1973-04       Impact factor: 5.532

2.  [Induction of experimental allergic encephalitis with synthetic human encephalitogenic substances].

Authors:  G Lamoureux; G Thibeault; G Richer; C Bernard
Journal:  Union Med Can       Date:  1972-04

3.  Immunologic determinants of experimental neurologic autoimmune disease and approaches to the multiple sclerosis problem.

Authors:  P Y Paterson; R S Fujinami; E D Day; V A Varitek; M D Pescovitz; J Kelly; L Lorand
Journal:  Trans Am Clin Climatol Assoc       Date:  1978

4.  Structural specificity of synthetic peptide adjuvant for induction of experimental allergic encephalomyelitis.

Authors:  Y Nagai; K Akiyama; S Kotani; Y Watanabe; T Shimono; T Shiba; S Kusumoto
Journal:  Cell Immunol       Date:  1978-01       Impact factor: 4.868

Review 5.  Myelin basic protein: structure, function and antigenic determinants.

Authors:  G A Hashim
Journal:  Immunol Rev       Date:  1978       Impact factor: 12.988

6.  Experimental allergic encephalomyelitis: synthesis of disease-inducing site of the basic protein.

Authors:  E H Eylar; J Caccam; J J Jackson; F C Westall; A B Robinson
Journal:  Science       Date:  1970-06-05       Impact factor: 47.728

7.  The development of experimental allergic encephalomyelitis with immunizing doses of myelin basic protein.

Authors:  G A Hashim; R D Sharpe; E Carvalho; L E Stevens
Journal:  Proc Soc Exp Biol Med       Date:  1975-07

8.  Induction of experimental allergic encephalomyelitis in PL/J and (SJL/J x PL/J)F1 mice by myelin basic protein and its peptides: localization of a second encephalitogenic determinant.

Authors:  R B Fritz; C H Chou; D E McFarlin
Journal:  J Immunol       Date:  1983-01       Impact factor: 5.422

9.  Experimental allergic encephalomyelitis: structural specificity of determinants for delayed hypersensitivity.

Authors:  G A Hashim; R D Sharpe
Journal:  Immunochemistry       Date:  1974-10

10.  Experimental allergic encephalitis. Dissociation of cellular immunity to brain protein and disease production.

Authors:  L E Spitler; C M Von Muller; H H Fudenberg; E H Eylar
Journal:  J Exp Med       Date:  1972-07-01       Impact factor: 14.307
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