Literature DB >> 608318

Evaluation of a charcoal-sorbitol mixture as an antidote for oral aspirin overdose.

M Mayersohn, D Perrier, A L Picchioni.   

Abstract

The preparation of charcoal in a 70% sorbitol solution results in a suspension that is more palatable and less gritty than an aqueous slurry of charcoal. Although the charcoal-sorbitol mixture may be slightly less effective in reducing the extent of aspirin absorption compared with a charcoal slurry, it may prove to be of particular value in those cases where acceptance of a charcoal slurry presents a problem.

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Year:  1977        PMID: 608318     DOI: 10.3109/15563657708988220

Source DB:  PubMed          Journal:  Clin Toxicol        ISSN: 0009-9309            Impact factor:   4.467


  7 in total

Review 1.  Activated charcoal in the treatment of drug overdose. An update.

Authors:  W Palatnick; M Tenenbein
Journal:  Drug Saf       Date:  1992 Jan-Feb       Impact factor: 5.606

2.  Comparative antidotal efficacy of activated charcoal tablets, capsules and suspension in healthy volunteers.

Authors:  H P Remmert; M Olling; W Slob; W F van der Giesen; A van Dijk; A G Rauws
Journal:  Eur J Clin Pharmacol       Date:  1990       Impact factor: 2.953

Review 3.  Cathartics and laxatives. Do they still have a place in management of the poisoned patient?

Authors:  M Shannon; S S Fish; F H Lovejoy
Journal:  Med Toxicol       Date:  1986 Jul-Aug

Review 4.  Clinical pharmacokinetics of oral activated charcoal in acute intoxications.

Authors:  P J Neuvonen
Journal:  Clin Pharmacokinet       Date:  1982 Nov-Dec       Impact factor: 6.447

Review 5.  Role of extracorporeal drug removal in acute theophylline poisoning. A review.

Authors:  A Heath; K Knudsen
Journal:  Med Toxicol Adverse Drug Exp       Date:  1987 Jul-Aug

Review 6.  Oral activated charcoal in the treatment of intoxications. Role of single and repeated doses.

Authors:  P J Neuvonen; K T Olkkola
Journal:  Med Toxicol Adverse Drug Exp       Date:  1988 Jan-Dec

7.  A modern view of excipient effects on bioequivalence: case study of sorbitol.

Authors:  M-L Chen; A B Straughn; N Sadrieh; M Meyer; P J Faustino; A B Ciavarella; B Meibohm; C R Yates; A S Hussain
Journal:  Pharm Res       Date:  2006-10-18       Impact factor: 4.580

  7 in total

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