| Literature DB >> 608177 |
G L Grove, B A Houghton, J W Cochran, E D Kress, V J Cristofalo.
Abstract
The effect of 14 micrometer hydrocortisone (HC) on the proliferative activity of various vertebrate cell lines has been measured. Such activity in human deploid cell line WI-38 was enhanced by HC addition whereas in a number of other vertebrate cell lines under identical conditions HC was inhibitory to growth. We examined the effects of HC on normal human diploid cells other than WI-38; some were stimulated, some inhibited and some were unresponsive. The results suggest that cells derived from different human tissues retain in vitro some aspects of their cell-specific hormonal responses.Entities:
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Year: 1977 PMID： 608177 DOI： 10.1016/0309-1651(77)90035-2
Source DB: PubMed Journal: Cell Biol Int Rep ISSN： 0309-1651