| Literature DB >> 60727 |
Abstract
The serum/CSF concentration ratio of alpha-2-macroglobulin is used as parameter to follow the development of the blood-CSF barrier throughout childhood. The decline of the protein permeability within the first year of life has all characteristics of a maturation process. The tightening of the barrier is thought to be the last stage of a continuous developmental process of capillaries. It is accompanied by a compositional shift in favour of small molecular serum proteins.Entities:
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Year: 1976 PMID: 60727 DOI: 10.1055/s-0028-1091621
Source DB: PubMed Journal: Neuropadiatrie ISSN: 0028-3797