Literature DB >> 606556

Insulin secretion in children with growth retardation.

B Boscherini, G Finocchi, O Lostia, G Mancuso, P Montani, A M Pasquino, E Rezza, J Rocchio, F Taggi, D Zorretta.   

Abstract

The effect of tolbutamide administration on insulin secretion was studied in 69 children with growth retardation. Diminished insulin secretion was found in all the patients, compared to the control group. This insulin deficit was most evident in patients with isolated, total GH deficiency and least evident in children with idiopathic short stature. Intermediate values were found in dwarfism due to isolated, partial GH deficiency. These results favour the hypothesis that hypoinsulinism contributes to the somatotropin deficiency in causing growth retardation.

Entities:  

Mesh：

Substances：

Year:  1977        PMID： 606556     DOI： 10.1007/bf00465562

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN： 0340-6199            Impact factor:   3.183


  17 in total

1.  [Insulin secretion in non-endocrine hyposomia and hyposomia with growth hormone deficiency].

Authors:  G M Molinatti; F Massara; F Camanni; V Martina
Journal:  Minerva Med       Date:  1975-03-14       Impact factor: 4.806

2.  EFFECT OF HUMAN GROWTH HORMONE ON INSULIN PRODUCTION IN PANHYPOPITUITARISM.

Authors:  R LUFT; E CERASI
Journal:  Lancet       Date:  1964-07-18       Impact factor: 79.321

3.  Immunoassay of insulin with insulin-antibody precipitate.

Authors:  C N HALES; P J RANDLE
Journal:  Biochem J       Date:  1963-07       Impact factor: 3.857

4.  A metabolic and hormonal basis for classifying ateliotic dwarfs.

Authors:  T J Merimee; J D Hall; D L Rimoin; V A McKusick
Journal:  Lancet       Date:  1969-05-10       Impact factor: 79.321

5.  Influence of long term growth hormone therapy on glucose tolerance and insulin secretion.

Authors:  K A Zuppinger; E E Joss
Journal:  Acta Paediatr Scand       Date:  1971-11

6.  Isolated human growth hormone deficiency. 3. Insulin secretion in sexual ateliotic dwarfism.

Authors:  T J Merimee; D Rabinowitz; D L Rimoin; V A McKusick
Journal:  Metabolism       Date:  1968-11       Impact factor: 8.694

7.  Diagnosis and management of growth retardation with special reference to the problem of hypopituitarism.

Authors:  A W Root; A M Bongiovanni; W R Eberlein
Journal:  J Pediatr       Date:  1971-05       Impact factor: 4.406

8.  Acute effects of human growth hormone on insulin secretion and glucose utilization in normal and growth hormone deficient subjects.

Authors:  L A Frohman; M H MacGillivray; T Aceto
Journal:  J Clin Endocrinol Metab       Date:  1967-04       Impact factor: 5.958

9.  Insulin response to intravenous glucagon in children with familial constitutional short stature.

Authors:  M Karp; Z Laron; M Doron
Journal:  Arch Dis Child       Date:  1975-10       Impact factor: 3.791

10.  Effect of low-dose human growth hormone on carbohydrate metabolism in children with hypopituitarism.

Authors:  G Costin; M D Kogut; S D Frasier
Journal:  J Pediatr       Date:  1972-05       Impact factor: 4.406
View more
  1 in total

Review 1.  Stunted growth with more or less normal appearance.

Authors:  J R Bierich; H Enders; U Heinrich; R Huenges; M B Ranke; D Schoenberg
Journal:  Eur J Pediatr       Date:  1982-12       Impact factor: 3.183
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.