Literature DB >> 606246

Clearance of human N-acetyl-beta-hexosaminidases from rat circulation.

T Bearpark, J L Stirling.   

Abstract

Human N-acetyl-beta-hexosaminidases As and P are probably sialylated since they are susceptible to neuraminidase attack. twhen infused into the circulation of a rat they are removed more slowly than the non-sialylated forms of the enzyme from tissue and urine.

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Year:  1977        PMID： 606246      PMCID： PMC1183790          DOI： 10.1042/bj1680435

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  20 in total

1.  The hydrolysis of Tay-Sachs ganglioside (TSG) by human N-acetyl-beta-D-hexosaminidase A.

Authors:  K Sandhoff
Journal:  FEBS Lett       Date:  1970-12-18       Impact factor: 4.124

2.  The existence of a second route for the transfer of certain glycoproteins from the circulation into the liver.

Authors:  R J Stockert; A G Morell; I H Scheinberg
Journal:  Biochem Biophys Res Commun       Date:  1976-02-09       Impact factor: 3.575

Review 3.  The significance of glycosylated proteins.

Authors:  P J Winterburn; C F Phelps
Journal:  Nature       Date:  1972-03-24       Impact factor: 49.962

4.  A recognition marker required for uptake of a lysosomal enzyme by cultured fibroblasts.

Authors:  S Hickman; L J Shapiro; E F Neufeld
Journal:  Biochem Biophys Res Commun       Date:  1974-03-15       Impact factor: 3.575

5.  Hexosaminidase-A and hexosaminidase-B: studies in Tay-Sachs' and Sandhoff's disease.

Authors:  S K Srivastava; E Beutler
Journal:  Nature       Date:  1973-02-16       Impact factor: 49.962

6.  Conversion of human hexosaminidase A to hexosaminidase "B" by crude Vibrio cholerae neuraminidase preparations: merthiolate is the active factor.

Authors:  P J Carmody; M C Rattazzi
Journal:  Biochim Biophys Acta       Date:  1974-11-05

7.  Differences between the N-acetyl hexosaminidase isozymes in serum and tissues.

Authors:  D M Swallow; D C Stokes; G Corney; H Harris
Journal:  Ann Hum Genet       Date:  1974-01       Impact factor: 1.670

8.  The role of sialic acid in determining the survival of glycoproteins in the circulation.

Authors:  A G Morell; G Gregoriadis; I H Scheinberg; J Hickman; G Ashwell
Journal:  J Biol Chem       Date:  1971-03-10       Impact factor: 5.157

9.  Investigations in enzyme replacement therapy in lipid storage diseases.

Authors:  R O Brady; P G Pentchev; A G Gal
Journal:  Fed Proc       Date:  1975-04

10.  N-acetyl-beta-hexosaminidase: role in the degradation of glycosaminoglycans.

Authors:  J N Thompson; A C Stoolmiller; R Matalon; A Dorfman
Journal:  Science       Date:  1973-08-31       Impact factor: 47.728
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  6 in total

Review 1.  Biochemistry and genetics of gangliosidoses.

Authors:  K Sandhoff; H Christomanou
Journal:  Hum Genet       Date:  1979       Impact factor: 4.132

2.  Recognition of human urine alpha-N-acetylglucosaminidase by rat hepatocytes. Involvement of receptors specific for galactose, mannose 6-phosphate and mannose.

Authors:  K Ullrich; R Basner; V Gieselmann; K Von Figura
Journal:  Biochem J       Date:  1979-05-15       Impact factor: 3.857

3.  Enzyme therapy in Fabry disease: differential in vivo plasma clearance and metabolic effectiveness of plasma and splenic alpha-galactosidase A isozymes.

Authors:  R J Desnick; K J Dean; G Grabowski; D F Bishop; C C Sweeley
Journal:  Proc Natl Acad Sci U S A       Date:  1979-10       Impact factor: 11.205

4.  Intermediate forms of human beta-N-acetylhexosaminidase lack activity towards 4-methylumbelliferyl beta-N-acetylglucosaminide 6-sulphate.

Authors:  T Beccari; C Emiliani; R Hosseini; A Orlacchio; J L Stirling
Journal:  Biochem J       Date:  1987-06-15       Impact factor: 3.857

5.  Secretion of beta-N-acetylglucosaminidase isoenzymes by normal human fibroblasts.

Authors:  P Willcox
Journal:  Biochem J       Date:  1978-08-01       Impact factor: 3.857

6.  Variant of GM2-gangliosidosis with hexosaminidase A having a severely changed substrate specificity.

Authors:  H J Kytzia; U Hinrichs; I Maire; K Suzuki; K Sandhoff
Journal:  EMBO J       Date:  1983       Impact factor: 11.598
  6 in total

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