| Literature DB >> 6057803 |
G S Bulmer, M D Sans, C M Gunn.
Abstract
Seven nonencapsulated mutants of Cryptococcus neoformans were isolated from an encapsulated strain of human origin. Initially, the mutants were avirulent for mice. After several months of subculturing, six of the seven isolates reverted to the encapsulated state and possessed varying degrees of virulence. The results of these experiments suggest that a strong correlation exists between the presence of a capsule and the virulence of C. neoformans.Entities:
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Year: 1967 PMID: 6057803 PMCID: PMC276850 DOI: 10.1128/jb.94.5.1475-1479.1967
Source DB: PubMed Journal: J Bacteriol ISSN: 0021-9193 Impact factor: 3.490