Literature DB >> 605628

Serum enzyme changes associated with carbon disulfide hepatotoxicity in experimental animals.

E A El-Dessoukey, R Awadallah, T H Mikhail.   

Abstract

Investigations were performed to evaluate the activities of serum glutamic oxalacetic and glutamic pyruvic transaminases, alkaline phosphatase and lactate-dehydrogenase enzymes in rats intoxicated by different doses of carbon disulfide. Serum GOT and GPT activities were elevated which may be due to CS2 effect on cell membrane permeability. Serum-alkaline-phosphatase activity showed also increment, which was again attributed to the liver affection. A significant rise in serum-lactate-dehydrogenase activity which was referred to be as a result of muscle-lactate dehydrogenase release into the blood circulation.

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Year:  1977        PMID： 605628     DOI： 10.1007/bf02023706

Source DB:  PubMed          Journal:  Z Ernahrungswiss        ISSN： 0044-264X


  13 in total

1.  [Histopathological note on chronic experimental carbon disulfide poisoning].

Authors:  A NUNZIANTE CESARO
Journal:  Folia Med (Napoli)       Date:  1954-06

2.  The clinical significance of transaminase activities of serum.

Authors:  F WROBLEWSKI
Journal:  Am J Med       Date:  1959-12       Impact factor: 4.965

3.  A study of carbon tetrachloride. II. The effect of carbon tetrachloride inhalation on serum and tissue enzymes.

Authors:  H H CORNISH; W D BLOCK
Journal:  Arch Environ Health       Date:  1960-08

4.  Alkaline phosphatase. I. Mechanism of action of Zn, Mg, glycine, versene and hydrogen ions.

Authors:  B H HOFSTEE
Journal:  Arch Biochem Biophys       Date:  1955-12       Impact factor: 4.013

5.  [Activity determination of enzymes of energy-producing metabolism in human serum and liver punctate in liver diseases; enzyme activity determination in human liver. III].

Authors:  E SCHMIDT; F W SCHMIDT; E WILDHIRT
Journal:  Klin Wochenschr       Date:  1958-03-15

6.  [Determination of sulfhydryl groups in blood serum following exposure to carbon disulfide].

Authors:  B SOUCEK; Z MADLO
Journal:  Bull Soc Chim Biol (Paris)       Date:  1955

7.  Influence of diet on serum alkaline phosphatase in rats and men.

Authors:  M SUKUMARAN; W L BLOOM
Journal:  Proc Soc Exp Biol Med       Date:  1953-12

8.  A CONVENIENT METHOD FOR DETERMINING SERUM AND BILE PHOSPHATASE ACTIVITY.

Authors:  E J King; A R Armstrong
Journal:  Can Med Assoc J       Date:  1934-10       Impact factor: 8.262

9.  The effect of the protein value of the diet on the neurological manifestations produced in rats by beta, beta-iminodipropionitrile.

Authors:  S R Morcos
Journal:  Br J Nutr       Date:  1967       Impact factor: 3.718

10.  The relationship of dietary factors to rat serum alkaline phosphatase. II. The effect of total food consumption, methionine, choline, and vitamin B12 in normal and alloxan diabetic adult rats.

Authors:  J TUBA; N B MADSEN
Journal:  Can J Med Sci       Date:  1952-02
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