| Literature DB >> 60516 |
P J Morris, W J Irvine, R S Gray, L J Duncan, H Vaughan, F J McCallum, C J Campbell, J W Farquhar.
Abstract
The frequency of HLA-B8 was significantly increased in pancreatic islet cell antibody (P.I.C.A)-positive patients (61%) compared with P.I.C.A.-negative patients (35%) and a control population (28%). This increased frequency of HLA-B8 was even more striking in diabetics in whom P.I.C.A. persisted for more than 5 years (71%). Thus the association of HLA-B8 with diabetes may be related to the presence of P.I.C.A. in these patients.Entities:
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Year: 1976 PMID： 60516 DOI： 10.1016/s0140-6736(76)92464-8
Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321