Literature DB >> 6049296

Inhibition of B virus in cell culture by 5-iodo-2'-deoxyuridine.

F A Miller.   

Abstract

The antimetabolite 5-iodo 2'-deoxyuridine (IDU) interferes with B virus replication in monolayers of cynomolgous monkey kidney, KB and HEp 2 cells. To determine the effect of this clinically active nucleoside in laboratory antiviral screening systems, several methods were compared. Most of the methods used were capable of detecting the activity of IDU at low levels.

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Year:  1967        PMID: 6049296      PMCID: PMC547048          DOI: 10.1128/am.15.4.733-735.1967

Source DB:  PubMed          Journal:  Appl Microbiol        ISSN: 0003-6919


  8 in total

1.  CELL CULTURE STUDIES ON ANTIVIRAL AGENTS. I. ACTION OF CYTOSINE ARABINOSIDE AND SOME COMPARISONS WITH 5-IODO-2-DEOXYURIDINE.

Authors:  D A BUTHALA
Journal:  Proc Soc Exp Biol Med       Date:  1964-01

2.  Effect of 5-iodo-2'-deoxyuridine on pseudorabies infection in rabbits.

Authors:  K E KOLB; R K BOWER; C E DUFFY
Journal:  Proc Soc Exp Biol Med       Date:  1963-06

3.  Cure of vaccinia infection by 5-iodo-2'-deoxyuridine.

Authors:  H E KAUFMAN; A B NESBURN; E D MALONEY
Journal:  Virology       Date:  1962-12       Impact factor: 3.616

4.  Clinical cure of herpes simplex keratitis by 5-iodo-2-deoxyuridine.

Authors:  H E KAUFMAN
Journal:  Proc Soc Exp Biol Med       Date:  1962-02

5.  Agar diffusion method for detection and bioassay of antiviral antibiotics.

Authors:  E C HERRMANN; J GABLIKS; C ENGLE; P L PERLMAN
Journal:  Proc Soc Exp Biol Med       Date:  1960-03

6.  Searching for antiviral materials from microbial fermentations.

Authors:  J Ehrlich; B J Sloan; F A Miller; H E Machamer
Journal:  Ann N Y Acad Sci       Date:  1965-07-30       Impact factor: 5.691

7.  Use of 5-iodo-2'-deoxyuridine (IDU) in treatment of herpes simplex keratitis.

Authors:  H KAUFMAN; E L MARTOLA; C DOHLMAN
Journal:  Arch Ophthalmol       Date:  1962-08

8.  INHIBITION BY 5-IODODEOXYURIDINE OF THE ONCOGENIC EFFECTS OF ADENOVIRUS TYPE 12 IN HAMSTERS.

Authors:  R J HUEBNER; W T LANE; A D WELCH; P CALABRESI; R W MCCOLLUM; W H PRUSOFF
Journal:  Science       Date:  1963-10-25       Impact factor: 47.728

  8 in total

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