Literature DB >> 604191

Somatostatin therapy of acute experimental pancreatitis.

P G Lankisch, H Koop, K Winckler, U R Fölsch, W Creutzfeldt.   

Abstract

Because somatostatin (SRIF) reduces exocrine pancreatic secretion, its effect on acute pancreatitis was investigated in rats. Linear SRIF reduced serum amylase and lipase but had no effect on pancreatic necrosis, oedema, leucocyte infiltration, and enzyme content. The mortality rate was not reduced. These results do not recommend the use of SRIF in the treatment of acute pancreatitis.

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Year:  1977        PMID： 604191      PMCID： PMC1411652          DOI： 10.1136/gut.18.9.713

Source DB:  PubMed          Journal:  Gut        ISSN： 0017-5749            Impact factor:   23.059


  16 in total

1.  Somatostatin suppresses secretin and pancreatic exocrine secretion.

Authors:  G Boden; M C Sivitz; O E Owen; N Essa-Koumar; J H Landor
Journal:  Science       Date:  1975-10-10       Impact factor: 47.728

2.  The preparation and properties of two new chromogenic substrates of trypsin.

Authors:  B F ERLANGER; N KOKOWSKY; W COHEN
Journal:  Arch Biochem Biophys       Date:  1961-11       Impact factor: 4.013

3.  An ultra-micro method for determination of amylase activity in blood serum.

Authors:  J R CLOSE; H V STREET
Journal:  Clin Chim Acta       Date:  1958-09       Impact factor: 3.786

4.  Determination of amylase activity in biological fluids.

Authors:  H V STREET; J R CLOSE
Journal:  Clin Chim Acta       Date:  1956 May-Jun       Impact factor: 3.786

5.  Experimental pancreatitis treated with glucagon or lactated Ringer solution.

Authors:  R E Condon; J H Woods; T L Poulin; W G Wagner; C A Pissiotis
Journal:  Arch Surg       Date:  1974-08

Review 6.  Testing pancreatic function.

Authors:  F P Brooks
Journal:  N Engl J Med       Date:  1972-02-10       Impact factor: 91.245

7.  The influence of glucagon on acute experimental pancreatitis in the rat.

Authors:  P G Lankisch; K Winckler; M Bokermann; H Schmidt; W Creutzfeldt
Journal:  Scand J Gastroenterol       Date:  1974-11       Impact factor: 2.423

8.  [Treatment of acute pancreatitis with glucagon. Report on a double blind study].

Authors:  H K Dürr; O Zelder; D Maroske; J C Bode
Journal:  Verh Dtsch Ges Inn Med       Date:  1976

9.  [Effect of somatostatin on betazole-stimulated gastric secretion and carbachol-stimulated pancreatic secretion and gall bladder contraction in man(author's transl)].

Authors:  P G Lankisch; R Arnold; W Creuzfeldt
Journal:  Dtsch Med Wochenschr       Date:  1975-09-05       Impact factor: 0.628

10.  Effects of somatostatin on exocrine and endocrine pancreatic function stimulated by intestinal hormones in man.

Authors:  H C Dollinger; S Raptis; E F Pfeiffer
Journal:  Horm Metab Res       Date:  1976-01       Impact factor: 2.936
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  20 in total

1.  Salutary and prophylactic effect of pentadecapeptide BPC 157 on acute pancreatitis and concomitant gastroduodenal lesions in rats.

Authors:  P Sikirić; S Seiwerth; Z Grabarević; R Rucman; M Petek; V Jagić; B Turković; I Rotkvić; S Mise; I Zoricić; L Jurina; P Konjevoda; M Hanzevacki; D Ljubanović; J Separović; M Gjurasin; M Bratulić; B Artuković; N Jelovac; G Buljat
Journal:  Dig Dis Sci       Date:  1996-07       Impact factor: 3.199

2.  Effects of somatostatin on acute pancreatitis induced in rats by injection of taurocholate and trypsin into a temporarily closed duodenal loop.

Authors:  P De Rai; C Franciosi; G M Confalonieri; R Biffi; B Andreoni; F Uggeri; A Malesci
Journal:  Int J Pancreatol       Date:  1988-07

3.  Effects of somatostatin on acute canine experimental pancreatitis.

Authors:  D E Schlarman; M C Beinfeld; C Andrus; D L Kaminski
Journal:  Int J Pancreatol       Date:  1987-08

4.  Influence of somatostatin in the evolution of acute pancreatitis. A prospective randomized study.

Authors:  L Luengo; V Vicente; F Gris; J M Coronas; J Escuder; J Ramón Gomez; J M Castellote
Journal:  Int J Pancreatol       Date:  1994-04

Review 5.  Changing concepts in the evaluation and treatment of acute severe pancreatitis.

Authors:  F Bonnet; N Rotman; P L Fagniez
Journal:  Intensive Care Med       Date:  1985       Impact factor: 17.440

Review 6.  Pharmacologic therapy for acute pancreatitis.

Authors:  Swetha Kambhampati; Walter Park; Aida Habtezion
Journal:  World J Gastroenterol       Date:  2014-12-07       Impact factor: 5.742

Review 7.  Acute and chronic pancreatitis. An update on management.

Authors:  P G Lankisch
Journal:  Drugs       Date:  1984-12       Impact factor: 9.546

8.  Effects of long-acting somatostatin analog (SMS 201-995) on eicosanoid synthesis and survival in rats with acute necrotizing pancreatitis.

Authors:  B van Ooijen; C J Tinga; W J Kort; F J Zijlstra; S W Lamberts; J H Wilson
Journal:  Dig Dis Sci       Date:  1992-09       Impact factor: 3.199

9.  Does the somatostatin analogue octreotide protect against ERCP induced pancreatitis?

Authors:  K F Binmoeller; A G Harris; R Dumas; C Grimaldi; J P Delmont
Journal:  Gut       Date:  1992-08       Impact factor: 23.059

10.  Antecedent long term ethanol consumption in combination with different diets alters the severity of experimental acute pancreatitis in rats.

Authors:  O J Rämö
Journal:  Gut       Date:  1987-01       Impact factor: 23.059
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