Literature DB >> 6039360

Studies of intestinal microflora. VI. Effect of x irradiation on the fecal microflora of the rat.

A S Klainer, S Gorbach, L Weinstein.   

Abstract

The effect of sublethal, midlethal, and lethal doses of total-body X irradiation on the fecal microbial population of the rat was studied. No changes were observed in animals receiving sublethal doses of X ray. Midlethal and lethal doses produced an increase in the numbers of fecal coliforms, staphylococci, streptococci, and fungi; these changes were transient in rats that survived, but were more marked and persisted during life in those that died. The possible role of these alterations in intestinal microflora in post-irradiation infection and in death is discussed.

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Year:  1967        PMID: 6039360      PMCID: PMC315050          DOI: 10.1128/jb.94.2.378-382.1967

Source DB:  PubMed          Journal:  J Bacteriol        ISSN: 0021-9193            Impact factor:   3.490


  12 in total

1.  Relation of the indigenous flora of the small intestine of the rat to post-irradiation bacteremia.

Authors:  J G VINCENT; R C VEOMETT; R F RILEY
Journal:  J Bacteriol       Date:  1955-01       Impact factor: 3.490

2.  Experimental infection and streptomycin treatment in irradiated mice.

Authors:  R Q MARSTON; L GONSHERY; I M ALDERMAN; W W SMITH
Journal:  Am J Physiol       Date:  1953-02

3.  Naturally occurring infections in untreated and streptomycin-treated x-irradiated mice.

Authors:  L GONSHERY; R Q MARSTON; W W SMITH
Journal:  Am J Physiol       Date:  1953-02

4.  Prophylactic antibiotic therapy in x-irradiated animals.

Authors:  W W SMITH; F SMITH; H J RUTH; H Y CANTER; M M GRENAN
Journal:  Am J Physiol       Date:  1953-02

5.  The treatment of postirradiation infection with antibiotics; an experimental study on mice.

Authors:  C P MILLER; C W HAMMOND; M TOMPKINS; G SHORTER
Journal:  J Lab Clin Med       Date:  1952-03

6.  The susceptibility of irradiated mice to infection as a function of post-irradiation time.

Authors:  I L SHECHMEISTER; V P BOND; M N SWIFT
Journal:  J Immunol       Date:  1952-01       Impact factor: 5.422

7.  The effect of terramycin on post-irradiation infection in mice.

Authors:  C W HAMMOND; C P MILLER
Journal:  Ann N Y Acad Sci       Date:  1950-09       Impact factor: 5.691

8.  Morphologic response of the mucosa of human small intestine to x-ray exposure.

Authors:  J S Trier; T H Browning
Journal:  J Clin Invest       Date:  1966-02       Impact factor: 14.808

9.  Studies on susceptibility to infection following ionizing radiation. II. Its estimation by oral inoculation at different times post irradiation.

Authors:  C W HAMMOND; M COLLING; D B COOPER; C P MILLER
Journal:  J Exp Med       Date:  1954-05-01       Impact factor: 14.307

10.  Studies on susceptibility to infection following ionizing radiation. V. Comparison of intraperitoneal and intravenous challenge at intervals following different doses of x-radiation.

Authors:  C P MILLER; C W HAMMOND; S K ANDERLE
Journal:  J Exp Med       Date:  1960-06-01       Impact factor: 14.307

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  5 in total

1.  Studies of intestinal microflora. VII. Effect of diet and fecal microbial flora on survival of animals exposed to x irradiation.

Authors:  A S Klainer; S Gorbach; L Weinstein
Journal:  J Bacteriol       Date:  1967-08       Impact factor: 3.490

Review 2.  Cancer chemotherapy-induced diarrhoea and constipation: mechanisms of damage and prevention strategies.

Authors:  Rachel J Gibson; Dorothy M K Keefe
Journal:  Support Care Cancer       Date:  2006-04-08       Impact factor: 3.603

3.  Relation between the faecal concentration of various potentially pathogenic microorganisms and infections in individuals (mice) with severely decreased resistance to infection.

Authors:  D van der Waaij; T M Tieleman-Speltie; A M de Roeck-Houben
Journal:  Antonie Van Leeuwenhoek       Date:  1978       Impact factor: 2.271

4.  Active components of intestinal bacteria for abdominal irradiation-induced inhibition of lung metastases.

Authors:  T Jibu; K Ando; T Matsumoto; S Koike; O Kobori; Y Morioka; S Kanegasaki
Journal:  Clin Exp Metastasis       Date:  1991 Nov-Dec       Impact factor: 5.150

5.  The gastrointestinal microflora of irradiated mice. I. Relationship of mucosa and microflora in weanling mice.

Authors:  E M Livstone; H M Spiro; T Hersh; M H Floch
Journal:  Yale J Biol Med       Date:  1970-06
  5 in total

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