Literature DB >> 6038165

Hydroxylation-induced migration: the NIH shift. Recent experiments reveal an unexpected and general result of enzymatic hydroxylation of aromatic compounds.

G Guroff, J W Daly, D M Jerina, J Renson, B Witkop, S Udenfriend.   

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Year:  1967        PMID： 6038165     DOI： 10.1126/science.157.3796.1524

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


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  71 in total

1.  Synthesis and evaluation of 4-quinazolinone compounds as potential antimalarial agents.

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Journal:  Eur J Med Chem       Date:  2010-05-24       Impact factor: 6.514

2.  History of Chemistry in the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

Authors:  Kenneth L Kirk; Kenneth A Jacobson
Journal:  Bull Hist Chem       Date:  2014-01-01

3.  Effect of pregnancy on the disposition of 2,2',3,5',6-pentachlorobiphenyl (PCB 95) atropisomers and their hydroxylated metabolites in female mice.

Authors:  Izabela Kania-Korwel; Christopher D Barnhart; Pamela J Lein; Hans-Joachim Lehmler
Journal:  Chem Res Toxicol       Date:  2015-08-13       Impact factor: 3.739

Review 4.  Rearrangement reactions catalyzed by cytochrome P450s.

Authors:  Paul R Ortiz de Montellano; Sidney D Nelson
Journal:  Arch Biochem Biophys       Date:  2010-10-29       Impact factor: 4.013

5.  Synthesis and evaluation of febrifugine analogues as potential antimalarial agents.

Authors:  Shuren Zhu; Li Meng; Quan Zhang; Lai Wei
Journal:  Bioorg Med Chem Lett       Date:  2006-01-24       Impact factor: 2.823

6.  Conversion of 7-dehydrocholesterol to 7-ketocholesterol is catalyzed by human cytochrome P450 7A1 and occurs by direct oxidation without an epoxide intermediate.

Authors:  Raku Shinkyo; Libin Xu; Keri A Tallman; Qian Cheng; Ned A Porter; F Peter Guengerich
Journal:  J Biol Chem       Date:  2011-08-03       Impact factor: 5.157

7.  Human Liver Microsomes Atropselectively Metabolize 2,2',3,4',6-Pentachlorobiphenyl (PCB 91) to a 1,2-Shift Product as the Major Metabolite.

Authors:  Eric Uwimana; Xueshu Li; Hans-Joachim Lehmler
Journal:  Environ Sci Technol       Date:  2018-04-27       Impact factor: 9.028

Review 8.  Kinetic deuterium isotope effects in cytochrome P450 oxidation reactions.

Authors:  F Peter Guengerich
Journal:  J Labelled Comp Radiopharm       Date:  2013-03-10       Impact factor: 1.921

9.  Aryl hydroxylation of the herbicide diclofop by a wheat cytochrome p-450 monooxygenase : substrate specificity and physiological activity.

Authors:  A Zimmerlin; F Durst
Journal:  Plant Physiol       Date:  1992-10       Impact factor: 8.340

10.  A novel mechanism for the NIH-shift.

Authors:  H Yagi; D M Jerina; G J Kasperek; T C Bruice
Journal:  Proc Natl Acad Sci U S A       Date:  1972-07       Impact factor: 11.205
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