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Literature DB >> 603764

Radioimmunoassay of human eosinophil cationic protein.

Abstract

A radioimmunosorbent assay has been developed which allows the detection in serum of a cationic protein derived from eosinophil granulocytes. In 34 healthy individuals the mean level was 31 microgram/1. with a range of 5-55 microgram/l. The serum concentration of 'eosinophil' cationic protein was correlated (p less than 0.001) to the number of eosinophil granulocytes in peripheral blood. Quantitation of 'eosinophil' cationic protein in serum might be useful in the study of eosinophil granulocyte turnover and function in vivo.

Entities: Gene Species

Mesh：

Substances：
Blood Proteins

Year: 1977 PMID： 603764 DOI： 10.1111/j.1365-2141.1977.tb01003.x

Source DB: PubMed Journal: Br J Haematol ISSN： 0007-1048 Impact factor: 6.998

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Cited

26 in total

1. Eosinophil cationic protein in atopic eczema.

Authors: T Jakob; K Hermann; J Ring
Journal: Arch Dermatol Res Date: 1991 Impact factor: 3.017

2. Interaction and complex-formation between the eosinophil cationic protein and alpha 2-macroglobulin.

Authors: C G Peterson; P Venge
Journal: Biochem J Date: 1987-08-01 Impact factor: 3.857

Review 3. Eosinophils in eosinophilic endomyocardial disease.

Authors: C J Spry
Journal: Postgrad Med J Date: 1986-06 Impact factor: 2.401

4. Evidence for eosinophil activation in bronchiectasis unrelated to cystic fibrosis and bronchopulmonary aspergillosis: discrepancy between blood eosinophil counts and serum eosinophil cationic protein levels.

Authors: C Kroegel; M Schüler; M Förster; R Braun; P R Grahmann
Journal: Thorax Date: 1998-06 Impact factor: 9.139

9. Purification and characterization of a new cationic protein--eosinophil protein-X (EPX)--from granules of human eosinophils.

Authors: C G Peterson; P Venge
Journal: Immunology Date: 1983-09 Impact factor: 7.397

10. Raised circulating levels of the eosinophil cationic protein in ankylosing spondylitis: relation with the inflammatory activity and the influence of sulphasalazine treatment.

Authors: N Feltelius; R Hällgren; P Venge
Journal: Ann Rheum Dis Date: 1987-05 Impact factor: 19.103

Radioimmunoassay of human eosinophil cationic protein.

1. Eosinophil cationic protein in atopic eczema.

2. Interaction and complex-formation between the eosinophil cationic protein and alpha 2-macroglobulin.

Review 3. Eosinophils in eosinophilic endomyocardial disease.

4. Evidence for eosinophil activation in bronchiectasis unrelated to cystic fibrosis and bronchopulmonary aspergillosis: discrepancy between blood eosinophil counts and serum eosinophil cationic protein levels.

5. Eosinophil cationic protein in inflammatory synovial effusions as evidence of eosinophil involvement.

6. Toxic effects of human eosinophil products on isolated rat heart cells in vitro.

7. The effect of platelet-activating factor on the responsiveness of the human nasal airway.

8. The pathogenesis of eosinophilic endomyocardial disease in patients with carcinomas of the lung.

9. Purification and characterization of a new cationic protein--eosinophil protein-X (EPX)--from granules of human eosinophils.

10. Raised circulating levels of the eosinophil cationic protein in ankylosing spondylitis: relation with the inflammatory activity and the influence of sulphasalazine treatment.