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Literature DB >> 603620

Induction of the alcohol-metabolizing pathway in the nematode Panagrellus redivivus: phenotypic effects.

Abstract

Panagrellus redivivus when placed in 7% ethanol or methanol becomes immobile. After 1 hr the animals resume normal swimming and will grow in alcohol. The ability to recover requires ADH activity and translation, but not transcription, as determined by inhibitor studies. Recovery decreases with longer-chain alcohols, with a greater recovery for branched rather than n-alcohols. Coincident with recovery is a threefold increase in alcohol dehydrogenase and aldehyde dehydrogenase activity. A model involving posttranscriptional control of the levels of these enzymes is presented.

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Year: 1977 PMID： 603620 DOI： 10.1007/bf00484508

Source DB: PubMed Journal: Biochem Genet ISSN： 0006-2928 Impact factor: 1.890

13 in total

1. A Rapid Method for Separating Larvae from Mixed Population of Panagrellus redivivus.

Authors: F Kriger; M R Kriger; M R Samoiloff
Journal: J Nematol Date: 1974-10 Impact factor: 1.402

2. Number and DNA content of nuclei in the free-living nematode Panagrellus silusiae at each stage during postembryonic development.

Authors: W C Sin; J Pasternak
Journal: Chromosoma Date: 1970 Impact factor: 4.316

3. Biological role of alcohol dehydrogenase in the tolerance of Drosophila melanogaster to aliphatic alochols: utilization of an ADH-null mutant.

Authors: J R David; C Bocquet; M F Arens; P Fouillet
Journal: Biochem Genet Date: 1976-12 Impact factor: 1.890

Induction of the alcohol-metabolizing pathway in the nematode Panagrellus redivivus: phenotypic effects.

1. A Rapid Method for Separating Larvae from Mixed Population of Panagrellus redivivus.

2. Number and DNA content of nuclei in the free-living nematode Panagrellus silusiae at each stage during postembryonic development.

3. Biological role of alcohol dehydrogenase in the tolerance of Drosophila melanogaster to aliphatic alochols: utilization of an ADH-null mutant.

4. Selection at the alcohol dehydrogenase locus in Drosophila melanogaster imposed by environmental ethanol.

5. Selection acting directly on an enzyme polymorphism.

6. The subcellular distribution and properties of aldehyde dehydrogenases in rat liver.

7. Nematode biochemistry. XIII. Peroxisomes in the free-living nematode, Turbatrix aceti.

8. The effect of growth inhibitors on postembryonic development in the free-living nematode, Pangrellus silusiae.

9. Alcohol dehydrogenase-negative mutants in Drosophila: defects at the structural locus?

10. The genetics of Caenorhabditis elegans.

1. Isolation of Caenorhabditis elegans mutants lacking alcohol dehydrogenase activity.