Literature DB >> 6035642

Morphological and biochemical studies of isolated mitochondria from fetal, neonatal, and adult liver and from neoplastic tissues.

H A Mintz, D H Yawn, B Safer, E Bresnick, A G Liebelt, Z R Blailock, E R Rabin, A Schwartz.   

Abstract

A combined morphological and biochemical investigation of mitochondria from developing and rapidly growing tissues ( tumors, fetal, and very early neonatal rat liver) revealed mitochondria which were deficient in respiratory control, showed no valinomycin induced K(+) accumulation or spontaneous Ca(++) uptake, and were unable to undergo a swelling-contraction cycle. Electron microscopic examination of fetal and neonatal livers and a mammary tumor revealed mitochondria which differed from controls with respect to matrix density and ability to undergo reversible structural changes. The importance of isolation and assay media in interpretation of results is emphasized.

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Year:  1967        PMID： 6035642      PMCID： PMC2107304          DOI： 10.1083/jcb.34.2.513

Source DB:  PubMed          Journal:  J Cell Biol        ISSN： 0021-9525            Impact factor:   10.539


  22 in total

1.  Studies on the mechanism by which anaerobiosis prevents swelling of mitochondria in vitro: effect of electron transport chain inhibitors.

Authors:  F E HUNTER; J F LEVY; J FINK; B SCHUTZ; F GUERRA; A HURWITZ
Journal:  J Biol Chem       Date:  1959-08       Impact factor: 5.157

2.  Energy pathways of hepatoma No. 5123.

Authors:  A C AISENBERG; H P MORRIS
Journal:  Nature       Date:  1961-09-23       Impact factor: 49.962

3.  Metabolic control mechanisms. II. Crossover phenomena in mitochondria of ascites tumor cells.

Authors:  B CHANCE; B HESS
Journal:  J Biol Chem       Date:  1959-09       Impact factor: 5.157

4.  Cellular metabolism and cancer: a review.

Authors:  S KIT; A C GRIFFIN
Journal:  Cancer Res       Date:  1958-07       Impact factor: 12.701

5.  Intracellular distribution of succinoxidase and cytochrome oxidase activities in normal mouse liver and in mouse hepatoma.

Authors:  W C SCHNEIDER; G H HOGEBOOM
Journal:  J Natl Cancer Inst       Date:  1950-02       Impact factor: 13.506

6.  Valinomycin and mitochondrial ion transport.

Authors:  E Ogata; H Rasmussen
Journal:  Biochemistry       Date:  1966-01       Impact factor: 3.162

7.  Swelling and shrinkage phenomena in liver mitochondria. IV. Reversible swelling changes linked to transport of monovalent cations stimulated by valinomycin.

Authors:  A Azzi; G F Azzone
Journal:  Biochim Biophys Acta       Date:  1966-03-07

8.  The effect of calcium ions on the glycolytic activity of Ehrlich ascites-tumour cells.

Authors:  F L Bygrave
Journal:  Biochem J       Date:  1966-11       Impact factor: 3.857

9.  Ultrastructural bases for metabolically linked mechanical activity in mitochondria. I. Reversible ultrastructural changes with change in metabolic steady state in isolated liver mitochondria.

Authors:  C R Hackenbrock
Journal:  J Cell Biol       Date:  1966-08       Impact factor: 10.539

10.  The effects of histones and other polycations on cellular energetics. IV. Further studies on the stimulation of mitochondrial oxygen consumption.

Authors:  C L Johnson; B Safer; A Schwartz
Journal:  J Biol Chem       Date:  1966-10-10       Impact factor: 5.157
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  16 in total

1.  The maturation of the inner membrane of foetal rat liver mitochondria.

Authors:  J K Pollak
Journal:  Biochem J       Date:  1975-09       Impact factor: 3.857

2.  Energy coupling and extramitochondrial electron transport in slices of Morris hepatoma 3924 A.

Authors:  T Galotti; E D'Amico; E Marchese; R Bompiani; T Terranova; M Russo
Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol       Date:  1974-03-14

3.  Changes in the proportions of two mitochondrial populations during the development of embryonic chick liver.

Authors:  J K Pollak; M Woog
Journal:  Biochem J       Date:  1971-07       Impact factor: 3.857

4.  Activity of some enzymes of nucleic acid metabolism in developing rat liver.

Authors:  E Köhler
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1972       Impact factor: 3.000

5.  Mitochondrial polymorphism in Amoeba proteus.

Authors:  C J Flickinger
Journal:  Protoplasma       Date:  1968       Impact factor: 3.356

6.  Studies on the transition of the cristal membrane from the orthodox to the aggregated configuration. 3. Loss of coupling ability of adrenal cortex mitochondria in the orthodox configuration.

Authors:  D W Allmann; J Munroe; T Wakabayashi; D E Green
Journal:  J Bioenerg       Date:  1970-10

7.  Electrophoretic and centrifugation behaviour of mitochondrial ribonucleic acid from Walker 256 carcinosarcoma.

Authors:  N F González-Cadavid; J L Pérez
Journal:  Biochem J       Date:  1975-02       Impact factor: 3.857

Review 8.  An Immunological Perspective on Neonatal Sepsis.

Authors:  Bernard Kan; Hamid Reza Razzaghian; Pascal M Lavoie
Journal:  Trends Mol Med       Date:  2016-03-15       Impact factor: 11.951

9.  Maturation in liver mitochondria of Ruthenium Red-sensitive calcium-ion-transport activity and the influence of glucagon administration in vivo and in utero.

Authors:  V Prpić; F L Bygrave
Journal:  Biochem J       Date:  1981-04-15       Impact factor: 3.857

10.  The isolation by isopycnic density-gradient centrifugation of two mitochondrial populations from livers of embryonic and fed and starved adult rats.

Authors:  J K Pollak; E A Munn
Journal:  Biochem J       Date:  1970-05       Impact factor: 3.857
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