Literature DB >> 60299

Study of the lysosomes by vital stains in normal keratocytes and in keratocytes from macular dystrophy of the cornea.

J François, V Victoria-Troncoso, P C Maudgal, A Victoria-Ihler.   

Abstract

The acridine orange is an excellent vital stain for the "in vivo" study of the lysosomal dynamics in cultured keratocytes. In normal keratocytes the lysosomes are mostly grouped around one or both nucleus poles. In keratocytes from macular dystrophy of the cornea there is a hypertrophy of the lysosomal system, which in vain tends to compensate for the consequences of the enzymatic deficiency.

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Year:  1976        PMID: 60299

Source DB:  PubMed          Journal:  Invest Ophthalmol        ISSN: 0020-9988


  5 in total

Review 1.  The cornea--structure and macromolecules in health and disease. A review.

Authors:  G K Klintworth
Journal:  Am J Pathol       Date:  1977-12       Impact factor: 4.307

2.  The synthesis of glycosaminoglycans by cultures of corneal stromal cells from patients with keratoconus.

Authors:  B Y Yue; J L Baum; J E Silbert
Journal:  J Clin Invest       Date:  1979-04       Impact factor: 14.808

Review 3.  Macular corneal dystrophy. Studies of sulfated glycosaminoglycans in corneal explant and confluent stromal cell cultures.

Authors:  G K Klintworth; C F Smith
Journal:  Am J Pathol       Date:  1977-10       Impact factor: 4.307

4.  Glycosaminoglycans in the human cornea: age-related changes.

Authors:  Elena Pacella; Fernanda Pacella; Giulio De Paolis; Francesca Romana Parisella; Paolo Turchetti; Giulia Anello; Carlo Cavallotti
Journal:  Ophthalmol Eye Dis       Date:  2015-01-27

5.  A newly synthesized platinum-based compound (PBC-II) increases chemosensitivity of HeLa ovarian cancer cells via inhibition of autophagy.

Authors:  Moureq Rashed Alotaibi; Homood Moqbel As Sobeai; Faten Abdullah Alaqil; Mashal Almutairi; Khalid Alhazzani; Adam A A Sulaiman; Anvarhusein A Isab; Nasser Hadal Alotaibi
Journal:  Saudi Pharm J       Date:  2019-10-16       Impact factor: 4.330

  5 in total

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