Literature DB >> 6028027

Tritiated thymidine: effect of decomposition by self-radiolysis on specificity as a tracer for DNA synthesis.

M Wand, E Zeuthen, E A Evans.   

Abstract

Tritiated thymidine undergoes decomposition by self-radiolysis. As shown by beta liquid-scintillation measurement and by autoradiography, the resultant breakdown products did not label DNA, but entered macromolecules, other than nucleic acid, contained in the cytoplasm. Caution should be exercised in using aged tritiated thymidine solutions.

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Year:  1967        PMID： 6028027     DOI： 10.1126/science.157.3787.436

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  10 in total

1.  Effectiveness of certain sterilizing agents for seedling incubation in radiothymidine.

Authors:  H A McQuade; A A Atchison; J T Parisi
Journal:  Plant Physiol       Date:  1969-02       Impact factor: 8.340

2.  Incorporation of labelled degradation products of radioactive thymine into non DNA material.

Authors:  M L Anderson
Journal:  Nucleic Acids Res       Date:  1978-11       Impact factor: 16.971

3.  Kinetics of gametogenesis. I. Comparative histological and autoradiographic studies of oocytes and transitional prospermatogonia during oogenesis and prespermatogenesis.

Authors:  B Hilscher; W Hilscher; B Bülthoff-Ohnolz; U Krämer; A Birke; H Pelzer; G Gauss
Journal:  Cell Tissue Res       Date:  1974       Impact factor: 5.249

4.  Structural proteins of simian virus 40: phosphoproteins.

Authors:  K B Tan; F Sokol
Journal:  J Virol       Date:  1972-11       Impact factor: 5.103

5.  Effect of denervation on the synthesis of ribonucleic acid and deoxyribonucleic acid in rat diaphragm muscle.

Authors:  K L Manchester; E J Harris
Journal:  Biochem J       Date:  1968-06       Impact factor: 3.857

6.  Localization of radioactivity in rat organs after oral administration of tritiated 8-methoxypsoralen in therapeutic doses.

Authors:  P F Engel; H C Wulf
Journal:  Arch Dermatol Res       Date:  1982       Impact factor: 3.017

7.  Epidermal growth factor stimulates DNA-synthesis of astrocytes in primary cerebellar cultures.

Authors:  A Leutz; M Schachner
Journal:  Cell Tissue Res       Date:  1981       Impact factor: 5.249

8.  Radioautographic studies of plaque-forming cells. I. Antigen-stimulated proliferation of plaque-forming cells.

Authors:  A M Koros; J M Mazur; M J Mowery
Journal:  J Exp Med       Date:  1968-08-01       Impact factor: 14.307

9.  The relationship between deoxyribonucleic acid replication and cell division in heat-synchronized tetrahymena.

Authors:  W R Jeffery; K D Stuart; J Frankel
Journal:  J Cell Biol       Date:  1970-09       Impact factor: 10.539

10.  Macromolecular syntheses related to the reproductive cyst of Tetrahymena patula.

Authors:  P R Gabe; L E De Bault
Journal:  J Cell Biol       Date:  1973-12       Impact factor: 10.539
  10 in total

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