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Literature DB >> 6018746

Blood ferrokinetics in normal man.

Abstract

The clearance of radioiron from plasma and its appearance in circulating erythrocytes in normal subjects are studied. The importance of correcting for plasma iron fluctuations and for mean body hematocrit is illustrated. The data are analyzed by probability theory to determine relationships between intravascular and extravascular iron. Two refluxes are described, one of about 7 particles of every 100 leaving the plasma, and the second of about 23. The return times of these are about 5 hours and 8 days, respectively.

Entities: Chemical Species

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Year: 1967 PMID： 6018746 PMCID： PMC297014 DOI： 10.1172/JCI105501

Source DB: PubMed Journal: J Clin Invest ISSN： 0021-9738 Impact factor: 14.808

13 in total

Blood ferrokinetics in normal man.

1. INCORPORATION OF RADIOIRON INTO MARROW HEME.

2. FERROKINETICS: A STUDY OF TRANSPORT IRON IN PLASMA.

3. STUDIES OF PLASMA FE59 DISAPPEARANCE--A MANIFESTATION OF INEFFECTIVE ERYTHROPOIESIS AND OF HEMOLYSIS.

4. STUDIES IN IRON KINETICS. I. INTERPRETATION OF FERROKINETIC DATA IN MAN.

5. The determination of iron in plasma or serum.

6. Studies of the metabolism of I-131-labeled human transferrin.

7. The quantitative determination of iron kinetics and hemoglobin synthesis in human subjects.

8. Iron and protein kinetics studied by means of doubly labeled human crystalline transferrin.

9. Plasma and red cell iron turnover in normal subjects and in patients having various hematopoietic disorders.

10. Ferrokinetics in normal persons and in patients having various erythropoietic disorders.

1. Pharmacodynamic Model of Hepcidin Regulation of Iron Homeostasis in Cynomolgus Monkeys.

2. The influence of circadian variations in plasma iron on the measure of plasma iron turnover.

3. Plasma radioiron kinetics in man: explanation for the effect of plasma iron concentration.

4. Androgens levels in plasma and urine of patients with virilizing congenital adrenal hyperplasia.

5. Magakaryocyte quantitation.

6. Ferrokinetics: a biologic model for plasma iron exchange in man.

7. Possible sources of error in the calculation of ferrokinetic parameters using Ricketts' triexponential model.

8. Disposal of plasma heme in normal man and patients with intravascular hemolysis.

9. Thrombokinetics in man.

10. Transferrin therapy ameliorates disease in beta-thalassemic mice.