| Literature DB >> 6018505 |
M M Cohen, M J Marinello, N Back.
Abstract
Addition of lysergic acid diethylamide to cultured human leukocytes resulted in a marked increase of chromosomal abnormalities. The distribution of chromosome breaks deviated significantly from random, with an accumulation of aberrations in chromosome No. 1. Cytogenetic investigation of a patient extensively treated with this drug over a 4-year period for paranoid schizophrenia showed a similar increase in chromosomal damage.Entities:
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Year: 1967 PMID： 6018505 DOI： 10.1126/science.155.3768.1417
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728