Literature DB >> 6018194

Evolution of immunoglobulins: structural homology of kappa and lambda Bence Jones proteins.

K Titani, M Wikler, F W Putnam.   

Abstract

The amino acid sequence of a human lamba chain has been determined. There are many identities in sequence with human kappa chains, but this intraspecies homology is less than the interspecies homology of kappa light chains of man and mouse. Structural relationships suggest a common evolutionary origin and early differentiation of light- and heavy-chain genes.

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Year:  1967        PMID： 6018194     DOI： 10.1126/science.155.3764.828

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  11 in total

1.  Identification of a gene locus for gamma-G-1 immunoglobulin H chains and its linkage to the H chain chromosome region in the mouse.

Authors:  J D Minna; G M Iverson; L A Herzenberg
Journal:  Proc Natl Acad Sci U S A       Date:  1967-07       Impact factor: 11.205

2.  Two types of lambda polypeptide chains in human immunoglobulins based on an amino acid substitution at position 190.

Authors:  E Appella; D Ein
Journal:  Proc Natl Acad Sci U S A       Date:  1967-05       Impact factor: 11.205

Review 3.  The structure of the heavy chain of immunoglobulin and its relevance to the nature of the antibody-combining site. The Second CIBA Medal Lecture.

Authors:  R R Porter
Journal:  Biochem J       Date:  1967-11       Impact factor: 3.857

Review 4.  [Bence Jones proteins].

Authors:  M Eulitz
Journal:  Blut       Date:  1969-02

Review 5.  [Genetic mechanisms of antibody formation].

Authors:  O Wetter; C G Schmidt
Journal:  Klin Wochenschr       Date:  1968-04-15

Review 6.  [On the trans-specific evolution of proteins].

Authors:  H Ritter
Journal:  Humangenetik       Date:  1968

7.  Evolutionary pattern of specificity regions in light chains of immunoglobulins.

Authors:  T H Jukes
Journal:  Biochem Genet       Date:  1969-04       Impact factor: 1.890

8.  The paucity of species-specific amino acid residues in the variable regions of human and mouse Bence-Jones proteins and its evolutionary and genetic implications.

Authors:  E A Kabat
Journal:  Proc Natl Acad Sci U S A       Date:  1967-05       Impact factor: 11.205

9.  Comparison of invariant residues in the variable and constant regions of human K, human L, and mouse K Bence-Jones proteins.

Authors:  E A Kabat
Journal:  Proc Natl Acad Sci U S A       Date:  1967-07       Impact factor: 11.205

10.  Unique features of the variable regions of Bence Jones proteins and their possible relation to antibody complementarity.

Authors:  E A Kabat
Journal:  Proc Natl Acad Sci U S A       Date:  1968-02       Impact factor: 11.205
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