Literature DB >> 6018

Regulation of pyruvate dehydrogenase and pyruvate dehydrogenase phosphate phosphatase activity in rat epididymal fat-pads. Effects of starvation, alloxan-diabetes and high-fat diet.

D Stansbie, R M Denton, B J Bridges, H T Pask, P J Randle.   

Abstract

1. Pyruvate dehydrogenase phosphate phosphatase activity in rat epididymal fat-pads was measured by using pig heart pyruvate dehydrogenase [32P]phosphate. About 80% was found to be extramitochondrial and therefore probably not directly concerned with the regulation of pyruvate dehydrogenase activity. The extramitochondrial activity was sensitive to activation by Ca2+, but perhaps less sensitive than the mitochondrial activity.

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Year:  1976        PMID： 6018      PMCID： PMC1172695          DOI： 10.1042/bj1540225

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  35 in total

1.  Dietary effect on lipogenesis in adipose tissue.

Authors:  F X HAUSBERGER; S W MILSTEIN
Journal:  J Biol Chem       Date:  1955-05       Impact factor: 5.157

2.  A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid.

Authors:  K BURTON
Journal:  Biochem J       Date:  1956-02       Impact factor: 3.857

3.  Hormonal regulation of pyruvate dehydrogenase.

Authors:  R L Jungas
Journal:  Metabolism       Date:  1971-01       Impact factor: 8.694

Review 4.  Regulation of the mammalian pyruvate dehydrogenase complex by covalent modification.

Authors:  O H Wieland; E A Siess; L Weiss; G Löffler; C Patzelt; R Portenhauser; U Hartmann; A Schirmann
Journal:  Symp Soc Exp Biol       Date:  1973

5.  Interconversion of pyruvate dehydrogenase in the isolated perfused rat liver.

Authors:  C Patzelt; G Löffler; O H Wieland
Journal:  Eur J Biochem       Date:  1973-02-15

6.  Secretion of and sensitivity to insulin in obese rats fed a high-fat diet.

Authors:  W J Malaisse; D Lemonnier; F Malaisse-Lagae; I M Mandelbaum
Journal:  Horm Metab Res       Date:  1969-01       Impact factor: 2.936

7.  Fatty acid synthesis by human adipose tissue.

Authors:  M S Patel; O E Owen; L I Goldman; R W Hanson
Journal:  Metabolism       Date:  1975-02       Impact factor: 8.694

8.  Regulation of heart muscle pyruvate dehydrogenase kinase.

Authors:  R H Cooper; P J Randle; R M Denton
Journal:  Biochem J       Date:  1974-12       Impact factor: 3.857

9.  Measurement of flow of carbon atoms from glucose and glycogen glucose to glyceride glycerol and glycerol in rat heart and epididymal adipose tissue. Effects of insulin, adrenaline and alloxan-diabetes.

Authors:  R M Denton; P J Randle
Journal:  Biochem J       Date:  1967-08       Impact factor: 3.857

10.  Calcium and magnesium ions as effectors of adipose-tissue pyruvate dehydrogenase phosphate phosphatase.

Authors:  D L Severson; R M Denton; H T Pask; P J Randle
Journal:  Biochem J       Date:  1974-05       Impact factor: 3.857
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  37 in total

1.  Acute effects in vivo of anti-insulin serum on rates of fatty acid synthesis and activities of acetyl-coenzyme A carboxylase and pyruvate dehydrogenase in liver and epididymal adipose tissue of fed rats.

Authors:  D Stansbie; R W Brownsey; M Crettaz; R M Denton
Journal:  Biochem J       Date:  1976-11-15       Impact factor: 3.857

2.  Comparison of the effects of insulin and adrenergic agonists on the phosphorylation of an acid-soluble 22 kDa protein in rat epididymal fat-pads and isolated fat-cells.

Authors:  T A Diggle; R M Denton
Journal:  Biochem J       Date:  1992-03-15       Impact factor: 3.857

3.  Insulin resistance of glucose metabolism in isolated brown adipocytes of lactating rats. Evidence for a post-receptor defect in insulin action.

Authors:  A F Burnol; S Ebner; J Kandé; J Girard
Journal:  Biochem J       Date:  1990-01-15       Impact factor: 3.857

4.  Insulin signaling requires glucose to promote lipid anabolism in adipocytes.

Authors:  James R Krycer; Lake-Ee Quek; Deanne Francis; Armella Zadoorian; Fiona C Weiss; Kristen C Cooke; Marin E Nelson; Alexis Diaz-Vegas; Sean J Humphrey; Richard Scalzo; Akiyoshi Hirayama; Satsuki Ikeda; Futaba Shoji; Kumi Suzuki; Kevin Huynh; Corey Giles; Bianca Varney; Shilpa R Nagarajan; Andrew J Hoy; Tomoyoshi Soga; Peter J Meikle; Gregory J Cooney; Daniel J Fazakerley; David E James
Journal:  J Biol Chem       Date:  2020-07-28       Impact factor: 5.157

5.  The mode of regulation of pyruvate dehydrogenase of lactating rat mammary gland. Effects of starvation and insulin.

Authors:  M A Baxter; H G Coore
Journal:  Biochem J       Date:  1978-08-15       Impact factor: 3.857

6.  Evidence that fatty acid synthesis in the interscapular brown adipose tissue of cold-adapted rats is increased in vivo by insulin by mechanisms involving parallel activation of pyruvate dehydrogenase and acetyl-coenzyme A carboxylase.

Authors:  J G McCormack; R M Denton
Journal:  Biochem J       Date:  1977-09-15       Impact factor: 3.857

7.  Lipogenic enzymes in rat maternal adipose tissue in the perinatal period.

Authors:  P A Sinnett-Smith; R G Vernon; R J Mayer
Journal:  Biochem J       Date:  1980-03-15       Impact factor: 3.857

8.  Branched-chain 2-oxo acid dehydrogenase interferes with the measurement of the activity and activity state of hepatic pyruvate dehydrogenase.

Authors:  G W Goodwin; R Paxton; S E Gillim; R A Harris
Journal:  Biochem J       Date:  1986-05-15       Impact factor: 3.857

9.  Persistence of the effect of insulin on pyruvate dehydrogenase activity in rat white and brown adipose tissue during the preparation and subsequent incubation of mitochondria.

Authors:  R M Denton; J G McCormack; S E Marshall
Journal:  Biochem J       Date:  1984-01-15       Impact factor: 3.857

10.  Dietary fish oil did not prevent sleep deprived rats from a reduction in adipose tissue adiponectin gene expression.

Authors:  Ana Barbosa Marcondes de Mattos; Mônica Jordão S Pinto; Cristiane Oliveira; Carolina Biz; Eliane Beraldi Ribeiro; Claudia Maria Oller do Nascimento; Monica Levy Andersen; Sergio Tufik; Lila Missae Oyama
Journal:  Lipids Health Dis       Date:  2008-11-05       Impact factor: 3.876
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