| Literature DB >> 6015532 |
R Y Moore, A Heller, R J Wurtman, J Axelrod.
Abstract
Activity of the melatoninforming enzyme, hydroxyindole-O-methyltransferase, in rat pineal is increased when the animal is exposed to continuous darkness, and it is decreased by exposure to continuous light. Response to environmental light is initiated in the retina and transmitted to the pineal by way of the central nervous system and the cervical sympathetics. The central visual pathway essential for mediation of this response is the inferior accessory optic tract. Visual pathways to thalamus and tectum do not participate in this response.Entities:
Mesh:
Substances:
Year: 1967 PMID: 6015532 DOI: 10.1126/science.155.3759.220
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728