| Literature DB >> 600179 |
Abstract
Constipation which is resistant to the usual range of laxatives is a troublesome undesirable effect of vincristine. Lactulose in doses up to 25 ml thrice daily proved to be a simple and effective treatment in six patients with refractory vincristine-induced constipation, and a successful prophylactic in two other patients. Palatable, and without any serious undesirable effects, lactulose can improve the quality of life for patients with a malignant tumour which is responsive to vincristine.Entities:
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Year: 1977 PMID： 600179 DOI： 10.5694/j.1326-5377.1977.tb114646.x
Source DB: PubMed Journal: Med J Aust ISSN： 0025-729X Impact factor: 7.738