Literature DB >> 60013

[The effect of D-penicillamine on experimental allergic arthritis in rabbits].

W Püschel, M Rosenkranz, G Geiler, B Caffier, P Stiehl, V Richter.   

Abstract

The effect of D-penicillamine on experimental allergic arthritis in rabbits (16 with arthritis and 15 controls) was investigated. After 40 days of treatment with D-penicillamine (intravenous) the arthritis had receded to a large extent. At the same time a maturation inhibition of the hematopoietic marrow had occurred in all the treated arthritic and control animals. The results suggest that D-penicillamine affects fast proliferating cells, to which the precursors of immunologically active cells in the synovial membrane also belong.

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Year:  1976        PMID： 60013

Source DB:  PubMed          Journal:  Z Rheumatol        ISSN： 0340-1855            Impact factor:   1.372


  5 in total

1.  Pharmacological studies of antigen-induced arthritis in BALB/c mice. II. The effects of second-line antirheumatic drugs and cytotoxic agents on the histopathological changes.

Authors:  I M Hunneyball; M J Crossley; M Spowage
Journal:  Agents Actions       Date:  1986-06

2.  The effects of oral D-penicillamine treatment on experimental arthritis and the associated immune response in rabbits. II. The effects on cellular parameters.

Authors:  I M Hunneyball; G A Stewart; D R Stanworth
Journal:  Immunology       Date:  1978-07       Impact factor: 7.397

3.  In vitro monocyte-lymphocyte interaction influenced by d-penicillamine.

Authors:  E De Vries; C J Haasnoot; J P Van der Weij; A Cats
Journal:  Clin Exp Immunol       Date:  1982-02       Impact factor: 4.330

4.  Effect of oral D-penicillamine treatment on experimental arthritis and associated immune responses in rabbits. III: Reduction of the monoarticular arthritis.

Authors:  I M Hunneyball; G A Stewart; D R Stanworth
Journal:  Ann Rheum Dis       Date:  1979-06       Impact factor: 19.103

5.  An investigation of the effect of anti-inflammatory and anti-rheumatoid drugs in cell-mediated immune arthritis in guinea-pigs by microfocal radiography.

Authors:  C H Cashin; N S Doherty; B L Jeffries; J C Buckland-Wright
Journal:  Br J Exp Pathol       Date:  1980-06
  5 in total

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