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Literature DB >> 599994

[Influence of duodenal reflux on the epithelium of the gastroenteral anastomosis (author's transl)].

P Schlag, H Meister, G Feyerabend, P Merkle.

Abstract

The cancerogenic effect of continous duodenal reflux on the gastric mucosa has been investigated in male Wistar-rats after gastrointestinal anastomosis. Groups of animals with gastroenterostomy without enteroenteral anastomosis and with Roux-en-y-anastomosis preventing duodenal reflux were treated with lower dosages of the cancerogenic Nitrosoguanidine. Proliferative mucosal alterations near the gastroenteral anastomosis were observed. In addition the gastric mucosa was characterized by adenomatous lesions caused by duodenal reflux. The changes detected were not influenced by Nitrosoguanidine and did not appear in cases of Roux-en-y-anastomosis.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1977 PMID： 599994 DOI： 10.1007/bf01254075

Source DB: PubMed Journal: Langenbecks Arch Chir ISSN： 0023-8236

22 in total

1. Sequential morphological changes in N-methyl-N'-nitro-N-nitrosoguanidine carcinogenesis in the glandular stomach of rats.

Authors: T Saito; K Inokuchi; S Takayama; T Sugimura
Journal: J Natl Cancer Inst Date: 1970-04 Impact factor: 13.506

9. Gastritis cystica polyposa. (Gastric mucosal prolapse at gastroenterostomy site, with cystic and infiltrative epithelial hyperplasia).

Authors: E R Littler; E Gleibermann
Journal: Cancer Date: 1972-01 Impact factor: 6.860

[Influence of duodenal reflux on the epithelium of the gastroenteral anastomosis (author's transl)].

1. Sequential morphological changes in N-methyl-N'-nitro-N-nitrosoguanidine carcinogenesis in the glandular stomach of rats.

2. EFFECT OF DUODENAL CONTENTS ON THE GASTRIC MUCOSA UNDER EXPERIMENTAL CONDITIONS.

3. [THE CLINICAL AND PATHOLOGIC-ANATOMICAL PICTURE OF CYSTIC GASTRITIS].

4. THE EFFECT OF BILE REFLUX ON THE GASTRIC MUCOSA.

5. Gastritis cystica and carcinoma arising in old gastrojejunostomy stoma.

6. On the corrosive properties of bile and pancreatic juice on living tissue in dogs.

7. Multiple polypoid cystic gastritis in old gastroenteric stoma.

8. Reaction of N-methyl-N'-nitro-N-nitroguanidine and N-methyl-N-nitroso-p-toluenesulfonamide with DNA in vitro.

9. Gastritis cystica polyposa. (Gastric mucosal prolapse at gastroenterostomy site, with cystic and infiltrative epithelial hyperplasia).

10. [Experimental gastric cancer (author's transl)].

1. Operation-sequel carcinoma of the stomach. Experimental studies of surgical techniques with or without resection.

2. [Animal experiments to assess the risk of cancer in the stomach after vagotomy (author's transl)].