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Literature DB >> 599573

Evaluation of the non-randomness of protein compositions.

Abstract

A method is described for assessing the non-randomness of protein compositions, based on the chi-squared statistic for the differences between the observed numbers of residues of each type and the numbers expected for a random distribution of codons. The analysis indicates that changes in at least 30% of the residues in natural proteins are selected against.

Mesh：

Substances：
Amino Acids
Codon
Proteins

Year: 1977 PMID： 599573 DOI： 10.1007/bf01764598

Source DB: PubMed Journal: J Mol Evol ISSN： 0022-2844 Impact factor: 2.395

8 in total

1. Tables of critical values for examining compositional non-randomness in proteins and nucleic acids.

Authors: M Laird; R Holmquist
Journal: J Mol Evol Date: 1975-03-24 Impact factor: 2.395

2. Compositional nonrandomness: a quantitatively conserved evolutionary invariant.

Authors: R Halmquist; H Moise
Journal: J Mol Evol Date: 1975-10-03 Impact factor: 2.395

3. Enzymatic synthesis of deoxyribonucleic acid. VIII. Frequencies of nearest neighbor base sequences in deoxyribonucleic acid.

Authors: J JOSSE; A D KAISER; A KORNBERG
Journal: J Biol Chem Date: 1961-03 Impact factor: 5.157

4. Deviations from compositional randomness in eukaryotic and prokaryotic proteins: the hypothesis of selective-stochastic stability and a principle of charge conservation.

Authors: R Holmquist
Journal: J Mol Evol Date: 1975-03-24 Impact factor: 2.395

5. The molecular evolution of cytochrome c in eukaryotes.

Authors: W M Fitch
Journal: J Mol Evol Date: 1976-06-23 Impact factor: 2.395

6. Nucleotide sequence of bacteriophage phi X174 DNA.

Authors: F Sanger; G M Air; B G Barrell; N L Brown; A R Coulson; C A Fiddes; C A Hutchison; P M Slocombe; M Smith
Journal: Nature Date: 1977-02-24 Impact factor: 49.962

7. Genetic variability maintained in a finite population due to mutational production of neutral and nearly neutral isoalleles.

Authors: M Kimura
Journal: Genet Res Date: 1968-06 Impact factor: 1.588

8. An improved method for determining codon variability in a gene and its application to the rate of fixation of mutations in evolution.

Authors: W M Fitch; E Markowitz
Journal: Biochem Genet Date: 1970-10 Impact factor: 1.890