Literature DB >> 598600

A large open multicentre trial of clomipramine (Anafranil) in the management of phobic disorders.

G Beaumont.   

Abstract

In a large, open, multicentre trial, conducted in general practice, 765 patients suffering from agoraphobia or social phobias were treated with clomipramine (Anafranil, Geigy Pharmaceuticals). Four hundred and eight patients completed a twelve-week course of treatment. Of 285 withdrawals, 139 were due to side-effects. Good results were obtained on all measures of phobias in those patients who completed the study, the improvements being of the order of 70-80%, and over 50% of patients being symptom-free.

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Year:  1977        PMID: 598600

Source DB:  PubMed          Journal:  J Int Med Res        ISSN: 0300-0605            Impact factor:   1.671


  7 in total

1.  A 2010 evidence-based algorithm for the pharmacotherapy of social anxiety disorder.

Authors:  Dan J Stein; David S Baldwin; Borwin Bandelow; Carlos Blanco; Leonardo F Fontenelle; Sing Lee; Hisato Matsunaga; David Osser; Murray B Stein; Michael van Ameringen
Journal:  Curr Psychiatry Rep       Date:  2010-10       Impact factor: 5.285

Review 2.  Social anxiety disorder : current treatment recommendations.

Authors:  Jacqueline E Muller; Liezl Koen; Soraya Seedat; Dan J Stein
Journal:  CNS Drugs       Date:  2005       Impact factor: 5.749

Review 3.  Overview of panic disorder.

Authors:  J C Ballenger
Journal:  Trans Am Clin Climatol Assoc       Date:  1994

Review 4.  Canadian clinical practice guidelines for the management of anxiety, posttraumatic stress and obsessive-compulsive disorders.

Authors:  Martin A Katzman; Pierre Bleau; Pierre Blier; Pratap Chokka; Kevin Kjernisted; Michael Van Ameringen; Martin M Antony; Stéphane Bouchard; Alain Brunet; Martine Flament; Sophie Grigoriadis; Sandra Mendlowitz; Kieron O'Connor; Kiran Rabheru; Peggy M A Richter; Melisa Robichaud; John R Walker
Journal:  BMC Psychiatry       Date:  2014-07-02       Impact factor: 3.630

Review 5.  Recent developments in the psychopharmacology of social phobia.

Authors:  J A Den Boer; I M van Vliet; H G Westenberg
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  1995       Impact factor: 5.270

6.  Psychopharmacological treatment of social phobia; a double blind placebo controlled study with fluvoxamine.

Authors:  I M van Vliet; J A den Boer; H G Westenberg
Journal:  Psychopharmacology (Berl)       Date:  1994-06       Impact factor: 4.530

7.  Optimal treatment of social phobia: systematic review and meta-analysis.

Authors:  John Canton; Kate M Scott; Paul Glue
Journal:  Neuropsychiatr Dis Treat       Date:  2012-05-03       Impact factor: 2.570

  7 in total

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